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Recombinant Human Caspase recruitment domain-containing protein 6 (CARD6), partial

Recombinant Human Caspase recruitment domain-containing protein 6 (CARD6), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

CARD6

Purity

>85% (SDS-PAGE)

Target Names

CARD6

Uniprot NO.

Q9BX69

Alternative Names

CARD 6; CARD containing inhibitor of Nod1 and Cardiak-induced NF kB activation; CARD6; CARD6_HUMAN; Caspase recruitment domain family; member 6; Caspase recruitment domain protein 6; Caspase recruitment domain-containing protein 6; CINCIN1; D730008L15

Species

Homo sapiens (Human)

Source

Yeast

Expression Region

2-1037

Target Protein Sequence

ATESTPSEI IERERKKLLE ILQHDPDSIL DTLTSRRLIS EEEYETLENV TDLLKKSRKL LILVQKKGEA TCQHFLKCLF STFPQSAAIC GLRHEVLKHE NTVPPQSMGA SSNSEDAFSP GIKQPEAPEI TVFFSEKEHL DLETSEFFRD KKTSYRETAL SARKNEKEYD TPEVTLSYSV EKVGCEVPAT ITYIKDGQRY EELDDSLYLG KEEYLGSVDT PEDAEATVEE EVYDDPEHVG YDGEEDFENS ETTEFSGEEP SYEGSETSLS LEEEQEKSIE ERKKVFKDVL LCLNMDRSRK VLPDFVKQFS LDRGCKWTPE SPGDLAWNFL MKVQARDVTA RDSILSHKVL DEDSKEDLLA GVENLEIRDI QTINPLDVLC ATMLCSDSSL QRQVMSNMYQ CQFALPLLLP DAENNKSILM LGAMKDIVKK QSTQFSGGPT EDTEKFLTLM KMPVISFVRL GYCSFSKSRI LNTLLSPAQL KLHKIFLHQD LPLLVLPRQI SDGLVEITWC FPDSDDRKEN PFFQKPVALA NLRGNLESFW TQFGFLMEVS SAVFFFTDCL GEKEWDLLMF LGEAAIERCY FVLSSQARES EEAQIFQRIL NLKPAQLLFW ERGDAGDRRK NMEGLQAALQ EVMFSSCLRC VSVEDMAALA RELGIQVDED FENTQRIQVS SGENMAGTAE GEGQQRHSQL KSSSKSQALM PIQEPGTQCE LSQNLQNLYG TPVFRPVLEN SWLFPTRIGG NFNHVSLKAS WVMGRPFGSE QRPKWFHPLP FQNAGAQGRG KSFGIQSFHP QIFYSGERFM KFSRVARGCH SNGTFGRLPR PICQHVQACP ERPQMMGTLE RSRAVASKIG HSYSLDSQPA RAVGKPWPQQ ACTRVTELTE ATGKLIRTSH IGKPHPQSFQ PAAATQKLRP ASQQGVQMKT QGGASNPALQ IGSHPMCKSS QFKSDQSNPS TVKHSQPKPF HSVPSQPKSS QTKSCQSQPS QTKPSPCKST QPKPSQPWPP QSKPSQPRPP QPKSSSTNPS QAKAHHSKAG QKRGGKH
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

May be involved in apoptosis.

Gene References into Functions

The increased expression of CARD6 in esophageal squamous cell carcinoma,gastric and colorectal adenocarcinoma suggested that neoexpression of CARD6 might be related to activation of NF-kappaB pathway. PMID:20025480
identification as a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways PMID:12775719
CARD6 is a regulator of NF-kappaB activation that modulates the functions of RICK protein PMID:16418290
review of the regulation of interactions of CARD6 with RICK and microtubules [review] PMID:16582588