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Recombinant Human Cadherin EGF LAG seven-pass G-type receptor 3 (CELSR3), partial

Recombinant Human Cadherin EGF LAG seven-pass G-type receptor 3 (CELSR3), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

CELSR3

Purity

>85% (SDS-PAGE)

Target Names

CELSR3

Uniprot NO.

Q9NYQ7

Species

Homo sapiens (Human)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Receptor that may have an important role in cell/cell signaling during nervous system formation.

Gene References into Functions

Study identifies four likely Tourette disorder risk genes with multiple de novo damaging variants in unrelated probands: WWC1 (WW and C2 domain containing 1), CELSR3 (Cadherin EGF LAG seven-pass G-type receptor 3), NIPBL (Nipped-B-like), and FN1 (fibronectin 1). PMID:28472652
marked reduction in the prominence of TUJ1 bundles in number, thickness, and length. Our results showed that deregulation of the planar cell polarity genes CELSR3 and FZD3 might disrupt the enteric innervation pattern PMID:27619161
A moderate positive correlation between CELSR3 and patient age was also evident. PMID:26838213
seven-transmembrane domain receptors Celsr3 and Fzd3, in particular, control the development of most longitudinal tracts in the central nervous system. [Review] PMID:25813877
CELSR3 promoter hypermethylation is associated with oral squamous cell carcinoma. PMID:25374236
CELSR3 was found to be selectively up-regulated in tumor stellate cells. PMID:20416094
CELSR3 is one of the core PCP signaling molecules. PMID:16273260