CELSR3 Antibody

Code: CSB-PA007948

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Size:

50μg100μg

US$119

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Species Reactivity: Human,Mouse,Rat

Raised in: Rabbit

Application: IF, ELISA

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Target Background

Product Details

Uniprot NO.

Q9NYQ7

Target Names

CELSR3

Alternative Names

Anchor protein antibody; Cadherin EGF LAG seven-pass G-type receptor 3 antibody; Cadherin family member 11 antibody; CDHF11 antibody; CELR3_HUMAN antibody; Celsr3 antibody; EGF like domain multiple 1 antibody; EGF-like protein 1 antibody; EGFL1 antibody; Epidermal growth factor-like protein 1 antibody; Flamingo antibody; Flamingo homolog 1 antibody; FMI1 antibody; hFmi1 antibody; MEGF2 antibody; Multiple EGF-like domains protein 2 antibody; Multiple epidermal growth factor-like domains protein 2 antibody; RESDA1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from the C-terminal region of Human CELSR3.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Tested Applications

IF, ELISA

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Receptor that may have an important role in cell/cell signaling during nervous system formation.

Gene References into Functions

Study identifies four likely Tourette disorder risk genes with multiple de novo damaging variants in unrelated probands: WWC1 (WW and C2 domain containing 1), CELSR3 (Cadherin EGF LAG seven-pass G-type receptor 3), NIPBL (Nipped-B-like), and FN1 (fibronectin 1). PMID:28472652
marked reduction in the prominence of TUJ1 bundles in number, thickness, and length. Our results showed that deregulation of the planar cell polarity genes CELSR3 and FZD3 might disrupt the enteric innervation pattern PMID:27619161
A moderate positive correlation between CELSR3 and patient age was also evident. PMID:26838213
seven-transmembrane domain receptors Celsr3 and Fzd3, in particular, control the development of most longitudinal tracts in the central nervous system. [Review] PMID:25813877
CELSR3 promoter hypermethylation is associated with oral squamous cell carcinoma. PMID:25374236
CELSR3 was found to be selectively up-regulated in tumor stellate cells. PMID:20416094
CELSR3 is one of the core PCP signaling molecules. PMID:16273260