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Recombinant Human CUB and sushi domain-containing protein 3 (CSMD3), partial

Recombinant Human CUB and sushi domain-containing protein 3 (CSMD3), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

CSMD3

Purity

>85% (SDS-PAGE)

Target Names

CSMD3

Uniprot NO.

Q7Z407

Alternative Names

CSMD3; KIAA1894CUB and sushi domain-containing protein 3; CUB and sushi multiple domains protein 3

Species

Homo sapiens (Human)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Involved in dendrite development.

Gene References into Functions

Nonsynonymous variants of CSMD3 is associated with familial colorectal cancer. PMID:21351276
CSMD3 encodes a protein with CUB and sushi multiple domains and is a candidate gene for benign adult familial myoclonic epilepsy on human chromosome 8q23.3-q24.1 PMID:12943675
Breakpoints on chromosomes 8 in both patients do not interrupt any known gene but both map in a region containing the CSMD3 gene, which thereby can be considered as a candidate for autistic spectrum disorders PMID:18270536
Single-nucleotide polymorphisms in CSMD3 is associated with prostate cancer risk in hispanic men. PMID:19528667
CSMD3 is deleted in a subject with combined tricho-rhino-phalangeal syndrome II with mental retardation and growth hormone deficiency. PMID:15523607
CSMD3 protein domain structure and the sequence of the cytoplasmic tail are highly conserved between mammals and fish. PMID:12906867

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Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

CSMD family

Tissue Specificity

Weakly expressed in most tissues, except in brain. Expressed at intermediate level in brain, including cerebellum, substantia nigra, thalamus, spinal cord, hippocampus and fetal brain. Also expressed in testis.

Database Links

HGNC: 19291

UNIGENE: Hs.91381

KEGG: hsa:114788

STRING: 9606.ENSP00000297405

OMIM: 608399

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