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Recombinant Human Bromodomain-containing protein 9 (BRD9)

Recombinant Human Bromodomain-containing protein 9 (BRD9)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

BRD9

Purity

>85% (SDS-PAGE)

Target Names

BRD9

Uniprot NO.

Q9H8M2

Species

Homo sapiens (Human)

Source

Yeast

Expression Region

1-597

Target Protein Sequence

MGKKHKKHKA EWRSSYEDYA DKPLEKPLKL VLKVGGSEVT ELSGSGHDSS YYDDRSDHER ERHKEKKKKK KKKSEKEKHL DDEERRKRKE EKKRKREREH CDTEGEADDF DPGKKVEVEP PPDRPVRACR TQPAENESTP IQQLLEHFLR QLQRKDPHGF FAFPVTDAIA PGYSMIIKHP MDFGTMKDKI VANEYKSVTE FKADFKLMCD NAMTYNRPDT VYYKLAKKIL HAGFKMMSKQ AALLGNEDTA VEEPVPEVVP VQVETAKKSK KPSREVISCM FEPEGNACSL TDSTAEEHVL ALVEHAADEA RDRINRFLPG GKMGYLKRNG DGSLLYSVVN TAEPDADEEE THPVDLSSLS SKLLPGFTTL GFKDERRNKV TFLSSATTAL SMQNNSVFGD LKSDEMELLY SAYGDETGVQ CALSLQEFVK DAGSYSKKVV DDLLDQITGG DHSRTLFQLK QRRNVPMKPP DEAKVGDTLG DSSSSVLEFM SMKSYPDVSV DISMLSSLGK VKKELDPDDS HLNLDETTKL LQDLHEAQAE RGGSRPSSNL SSLSNASERD QHHLGSPSRL SVGEQPDVTH DPYEFLQSPE PAASAKT
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Plays a role in chromatin remodeling and regulation of transcription. Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Orchestrates also the RAD51-RAD54 complex formation and thereby plays a role in homologous recombination (HR).

Gene References into Functions

The bromodomains of BRD9, CECR2, and the second bromodomain of TAF1 recognize the longer butyryl mark on histones. In addition, the TAF1 second bromodomain is capable of binding crotonyl marks. PMID:26365797

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Database Links

HGNC: 25818

UNIGENE: Hs.449278

KEGG: hsa:65980

STRING: 9606.ENSP00000419765

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