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Recombinant Human Alkaline phosphatase, germ cell type (ALPG)

Recombinant Human Alkaline phosphatase, germ cell type (ALPG)

E.coli
Baculovirus

Code
MSDS	MSDS
Size	Pls inquire
Source
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

ALPPL2

Uniprot NO.

P10696

Species

Homo sapiens (Human)

Source

Yeast

Expression Region

20-503

Target Protein Sequence

I IPVEEENPDF WNRQAAEALG AAKKLQPAQT AAKNLIIFLG DGMGVSTVTA ARILKGQKKD KLGPETFLAM DRFPYVALSK TYSVDKHVPD SGATATAYLC GVKGNFQTIG LSAAARFNQC NTTRGNEVIS VMNRAKKAGK SVGVVTTTRV QHASPAGAYA HTVNRNWYSD ADVPASARQE GCQDIATQLI SNMDIDVILG GGRKYMFPMG TPDPEYPDDY SQGGTRLDGK NLVQEWLAKH QGARYVWNRT ELLQASLDPS VTHLMGLFEP GDMKYEIHRD STLDPSLMEM TEAALLLLSR NPRGFFLFVE GGRIDHGHHE SRAYRALTET IMFDDAIERA GQLTSEEDTL SLVTADHSHV FSFGGYPLRG SSIFGLAPGK ARDRKAYTVL LYGNGPGYVL KDGARPDVTE SESGSPEYRQ QSAVPLDGET HAGEDVAVFA RGPQAHLVHG VQEQTFIAHV MAFAACLEPY TACDLAPRAG TTD

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free

Buffer

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Description

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Target Background

Function

Alkaline phosphatase that can hydrolyze various phosphate compounds.

Gene References into Functions

aptamer-mediated identification of ALPPL-2 on the cell surface and cell secretions of pancreatic cancer cells supports its potential use in the serum- and membrane-based diagnosis of PDAC PMID:23467613
These results indicate that IAP is strongly involved in chylomicron formation and fatty acid metabolism might change among ABO blood type. PMID:16412386
Premature induction of hypertrophy-related molecules (type X collagen and matrix metalloproteinase 13) occurred before production of type II collagen and was followed by up-regulation of alkaline phosphatase activity. PMID:17009260

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Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.

Protein Families

Alkaline phosphatase family

Tissue Specificity

Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors.

Database Links

HGNC: 441

UNIGENE: Hs.333509

KEGG: hsa:251

STRING: 9606.ENSP00000295453