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Recombinant Human ATP-binding cassette sub-family A member 6 (ABCA6), partial

Recombinant Human ATP-binding cassette sub-family A member 6 (ABCA6), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

ABCA6

Purity

>85% (SDS-PAGE)

Target Names

ABCA6

Uniprot NO.

Q8N139

Alternative Names

ABC transporter ABCA6; ABCA 6; ABCA6; ABCA6_HUMAN; ATP binding cassette A6; ATP binding cassette sub family A (ABC1) member 6; ATP binding cassette sub family A member 6; ATP-binding cassette sub-family A member 6; EST155051; FLJ43498

Species

Homo sapiens (Human)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Probable transporter which may play a role in macrophage lipid transport and homeostasis.

Gene References into Functions

A rare missense variant in ABCA6 (rs77542162, p.Cys1359Arg, frequency 0.034), found in a Dutch population, is predicted to be deleterious with respect to blood cholesterol levels. PMID:25751400
These data provide evidence for an essential role of FoxO proteins in the transcription of ABCA6 in human vascular endothelial cells. PMID:24028821

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Subcellular Location

Golgi apparatus membrane; Multi-pass membrane protein.

Protein Families

ABC transporter superfamily, ABCA family

Tissue Specificity

Widely expressed with higher expression in liver.

Database Links

HGNC: 36

UNIGENE: Hs.709514

KEGG: hsa:23460

STRING: 9606.ENSP00000284425