ABCA6 Antibody

CSB-PA988363

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Size:

100μl

US$297

Quantity:

Species Reactivity: Human

Raised in: Rabbit

Application: ELISA,WB

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Target Background

Product Details

Uniprot NO.

Q8N139

Target Names

ABCA6

Alternative Names

ABC transporter ABCA6 antibody; ABCA 6 antibody; ABCA6 antibody; ABCA6_HUMAN antibody; ATP binding cassette A6 antibody; ATP binding cassette sub family A (ABC1) member 6 antibody; ATP binding cassette sub family A member 6 antibody; ATP-binding cassette sub-family A member 6 antibody; EST155051 antibody; FLJ43498 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from C-terminal of Human ABCA6.

Immunogen Species

Homo sapiens (Human)

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Tested Applications

ELISA,WB

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Protocols

ELISA Protocol Western Blotting(WB) Protocol

Datasheet & COA

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Images

Western blot analysis of extracts from 293 cells, using ABCA6 antibody.

Description

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Target Background

Function

Probable transporter which may play a role in macrophage lipid transport and homeostasis.

Gene References into Functions

A rare missense variant in ABCA6 (rs77542162, p.Cys1359Arg, frequency 0.034), found in a Dutch population, is predicted to be deleterious with respect to blood cholesterol levels. PMID:25751400
These data provide evidence for an essential role of FoxO proteins in the transcription of ABCA6 in human vascular endothelial cells. PMID:24028821

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Subcellular Location

Golgi apparatus membrane; Multi-pass membrane protein.

Protein Families

ABC transporter superfamily, ABCA family

Tissue Specificity

Widely expressed with higher expression in liver.

Database Links

HGNC: 36

UNIGENE: Hs.709514

KEGG: hsa:23460

STRING: 9606.ENSP00000284425