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Recombinant Drosophila melanogaster Maternal effect protein staufen (stau), partial

Recombinant Drosophila melanogaster Maternal effect protein staufen (stau), partial

Baculovirus
Mammalian cell

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

stau

Uniprot NO.

P25159

Alternative Names

stau; CG5753; Maternal effect protein staufen

Species

Drosophila melanogaster (Fruit fly)

Source

Yeast

Expression Region

1-1026

Target Protein Sequence

MQHNVHAARP APHIRAAHHH SHSHAHMHLH PGMEQHLGPS LQQQQQPPPP PQQPPHRDLH ARLNHHHLHA QQQQQQQTSS NQAGAVAAAG AAYHHGNINS NSGSNISSNS NQMQKIRQQH QHLSSSNGLL GNQPPGPPPQ AFNPLAGNPA ALAYNQLPPH PPHHMAAHLG SYAAPPPHYY MSQAKPAKYN HYGSNANSNS GSNNSNSNYA PKAILQNTYR NQKVVVPPVV QEVTPVPEPP VTTNNATTNS TSNSTVIASE PVTQEDTSQK PETRQEPASA DDHVSTGNID ATGALSNEDT SSSGRGGKDK TPMCLVNELA RYNKITHQYR LTEERGPAHC KTFTVTLMLG DEEYSADGFK IKKAQHLAAS KAIEETMYKH PPPKIRRSEE GGPMRTHITP TVELNALAMK LGQRTFYLLD PTQIPPTDSI VPPEFAGGHL LTAPGPGMPQ PPPPPAYALR QRLGNGFVPI PSQPMHPHFF HGPGQRPFPP KFPSRFALPP PLGAHVHHGP NGPFPSVPTP PSKITLFVGK QKFVGIGRTL QQAKHDAAAR ALQVLKTQAI SASEEALEDS MDEGDKKSPI SQVHEIGIKR NMTVHFKVLR EEGPAHMKNF ITACIVGSIV TEGEGNGKKV SKKRAAEKML VELQKLPPLT PTKQTPLKRI KVKTPGKSGA AAREGSVVSG TDGPTQTGKP ERRKRLNPPK DKLIDMDDAD NPITKLIQLQ QTRKEKEPIF ELIAKNGNET ARRREFVMEV SASGSTARGT GNSKKLAKRN AAQALFELLE AVQVTPTNET QSSEECSTSA TMSAVTAPAV EATAEGKVPM VATPVGPMPG ILILRQNKKP AKKRDQIVIV KSNVESKEEE ANKEVAVAAE ENSNNSANSG DSSNSSSGDS QATEAASESA LNTSTGSNTS GVSSNSSNVG ANTDGNNHAE SKNNTESSSN STSNTQSAGV HMKEQLLYLS KLLDFEVNFS DYPKGNHNEF LTIVTLSTHP PQICHGVGKS SEESQNDAAS NALKILSKLG LNNAMK
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

RNA-binding protein which forms ribonucleoprotein complexes (RNPs) that play critical roles in the localization, translational repression and turnover of RNAs during embryogenesis, neurotransmission and neurogenesis. In the oocyte, essential for the localization of both the osk/oskar mRNA to the posterior pole and bcd/bicoid RNA to the anterior pole, and is therefore required for the correct anterior-posterior patterning of the developing embryo. Association with osk or bcd at their respective poles, appears to promote the formation and stabilization of the ribonucleoprotein complexes. Integral component of diverse neuritic ribonucleoprotein complexes (RNPs) that mediate the transport, translation and turnover of neuronal RNAs during neuorgenesis and the translation repression of synaptic transcripts in preparation for their dendritic targeting.

Gene References into Functions

The role of Miranda in the localization of Staufen during the division of neuroblasts is described. PMID:26423004
Staufen targets coracle mRNA to Drosophila neuromuscular junctions and regulates GluRIIA synaptic accumulation and bouton number. PMID:24951879
establishment of developmental precision and proportions in the early Drosophila embryo PMID:11845210
role in long-term memory PMID:12593794
Miranda has a role in coupling oskar mRNA/Staufen complexes to the bicoid mRNA localization pathway PMID:16905128