Recombinant Dog Interleukin-2 (IL2)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

IL2

Purity

>85% (SDS-PAGE)

Target Names

IL2

Uniprot NO.

Q29416

Species

Canis lupus familiaris (Dog) (Canis familiaris)

Source

Yeast

Expression Region

21-155

Target Protein Sequence

APITSSSTKE TEQQMEQLLL DLQLLLNGVN NYENPQLSRM LTFKFYTPKK ATEFTHLQCL AEELKNLEEV LGLPQSKNVH LTDTKELISN MNVTLLKLKG SETSYNCEYD DETATITEFL NKWITFCQSI FSTLT
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.

Gene References into Functions

immunoreactivities of inflammatory cytokines, such as interleukin (IL)-2, its receptor (IL-2R), IL-4 and its receptor (IL-4R) in the cervical and lumbar spinal cord of young adult and aged beagle dogs, were compared. PMID:23605681
In dogs with leishmaniasis, there was high expression of genes encoding IL-2 in lymph nodes. PMID:21511273

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Subcellular Location

Secreted.

Protein Families

IL-2 family

Database Links

UNIGENE: Cfa.7

KEGG: cfa:403989

STRING: 9615.ENSCAFP00000005941

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