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Recombinant Danio rerio Mothers against decapentaplegic homolog 5 (smad5)

Recombinant Danio rerio Mothers against decapentaplegic homolog 5 (smad5)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

smad5

Purity

>85% (SDS-PAGE)

Target Names

smad5

Uniprot NO.

Q9W7E7

Species

Danio rerio (Zebrafish) (Brachydanio rerio)

Source

Yeast

Expression Region

1-464

Target Protein Sequence

MTSMSSLFSF TSPAVKRLLG WKQGDEEEKW AEKAVDALVK KLKKKKGAME DLEKALSSPG QPSKCVTIPR SLDGRLQVSH RKGLPHVIYC RVWRWPDLQS HHELKPLEVC EYPFGSKQKE VCINPYHYKR VESPVLPPVL VPRHSEFNPQ HSLLVQFRNL SHNEPHMPLN ATFPESFQQH SGGSSFPISP NSPYPPSPAS SGTYPNSPAS SGPSSPFQLP ADTPPPAYMP PDEQMGQDGS QSMETGSSLA PQNMPRGDVQ PVEYQEPSHW CSIVYYELNN RVGEAYHASS TSVLVDGFTD PSNNKNRFCL GLLSNVNRNS TIENTRRHIG KGVHLYYVGG EVYAECLSDT SIFVQSRNCN YHHGFHPTTV CKIPSGCSLK IFNNQEFAQL LAQSVNHGFE AVYELTKMCT IRMSFVKGWG AEYHRQDVTS TPCWIEVHLH GPLQWLDKVL TQMGSPLNPI SSVS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Involved in ventralization. May mediate Bmp2b signaling during early phases of embryonic dorsal-ventral pattern formation. Required for initiation of Smad1 expression during gastrulation.

Gene References into Functions

TGFbeta1a regulates zebrafish posterior lateral line formation via Smad5 mediated pathway. PMID:25603803
Alk3 and Alk3b, as well as SMAD5, are essential cellular mediators of BMP signaling in zebrfish. PMID:24608800
Data show that patterning of the eye primordia in Smad5-deficient embryos starts during blastula and early gastrula stages. PMID:12701105
Data show that Smad5 expression is ubiquitous during testis development but becomes cell-specific in the adult. PMID:18069690