smad5 Antibody

Code: CSB-PA894791XA01DIL

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Danio rerio (Zebrafish) (Brachydanio rerio)

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Product Details
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Target Background

Product Details

Uniprot NO.

Q9W7E7

Target Names

smad5

Alternative Names

smad5 antibody; madh5 antibody; sbn antibody; Mothers against decapentaplegic homolog 5 antibody; MAD homolog 5 antibody; Mothers against DPP homolog 5 antibody; Protein somitabun antibody; SMAD family member 5 antibody; SMAD 5 antibody; Smad5 antibody

Raised in

Rabbit

Species Reactivity

Danio rerio (Zebrafish) (Brachydanio rerio)

Immunogen

Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) smad5 protein

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Involved in ventralization. May mediate Bmp2b signaling during early phases of embryonic dorsal-ventral pattern formation. Required for initiation of Smad1 expression during gastrulation.

Gene References into Functions

TGFbeta1a regulates zebrafish posterior lateral line formation via Smad5 mediated pathway. PMID:25603803
Alk3 and Alk3b, as well as SMAD5, are essential cellular mediators of BMP signaling in zebrfish. PMID:24608800
Data show that patterning of the eye primordia in Smad5-deficient embryos starts during blastula and early gastrula stages. PMID:12701105
Data show that Smad5 expression is ubiquitous during testis development but becomes cell-specific in the adult. PMID:18069690