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Recombinant Bovine Thyrotropin receptor (TSHR), partial

Recombinant Bovine Thyrotropin receptor (TSHR), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

TSHR

Purity

>85% (SDS-PAGE)

Target Names

TSHR

Uniprot NO.

Q27987

Alternative Names

TSHR; Thyrotropin receptor; Thyroid-stimulating hormone receptor; TSH-R

Species

Bos taurus (Bovine)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

Gene References into Functions

Localization of thyrotropin receptor and thyroglobulin in the bovine corpus luteum. PMID:19553036
analysis of activation switch in the thyrotropin receptor PMID:15722344
Rhes can interfere with the functional activity of wt and mutated TSHr. PMID:17556863
Increased receptor binding by bovine (b) TSH bound to monoclonal antibody to bTSHbeta-subunit. PMID:18202525
the hinge region represents an extracellular intermediate connector for both hormone binding and signal transduction of the thyroid stimulating hormone receptor PMID:18441013