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Recombinant Bovine Platelet-activating factor receptor (PTAFR), partial

Recombinant Bovine Platelet-activating factor receptor (PTAFR), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

PTAFR

Purity

>85% (SDS-PAGE)

Target Names

PTAFR

Uniprot NO.

Q9TTY5

Alternative Names

PTAFR; PAFR; Platelet-activating factor receptor; PAF-R; PAFr

Species

Bos taurus (Bovine)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. May be involved in the morphological and physical modifications of the oviduct and uterus during the estrus cycle and early pregnancy.

Gene References into Functions

PAF and luteinizing hormone signaling plays an important role in regulating the production of excessive oxidants. PMID:19565634
The results provide clear evidence for expression of PAFr in bovine granulosa cells and its functional involvement in PAF/PAFr-mediated stimulation of cell recruitment. PMID:18021181

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Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor 1 family

Tissue Specificity

Found in oviductal epithelial and stroma cells. Levels in the oviduct are raised at days 2-4 of both pregnancy and of the estrus cycle. In the endometrium, localization is predominantly to the apical borders of glandular and luminal epithelial cells. Expr

Database Links

UNIGENE: Bt.63372

KEGG: bta:518283

STRING: 9913.ENSBTAP00000038567

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