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Recombinant Bovine Beta-2 adrenergic receptor (ADRB2), partial

Recombinant Bovine Beta-2 adrenergic receptor (ADRB2), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

ADRB2

Purity

>85% (SDS-PAGE)

Target Names

ADRB2

Uniprot NO.

Q28044

Species

Bos taurus (Bovine)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

Gene References into Functions

These results indicate dependence of hepatic glucocorticoid and adrenergic receptors on stage of maturation in neonatal calves and emphasize the association of alpha1-adrenergic receptor and glucocorticoid receptor with neonatal glucose and lipid metabolism. PMID:25497806
ADRb2 shows lipid scrambling activity. PMID:25296113
relationship between luteal concentrations of oxytocin (OT), noradrenaline (NA), progesterone (P4), oxytocin receptors (OT-R) and beta(2)-adrenoreceptors (beta(2)-R) gene expression and their protein level throughout the estrous cycle PMID:20149890
of the beta-adrenergic receptors, adrenergic beta(2)-receptor type was most highly expressed in the mammary gland of dairy cows followed by beta(1) and beta(3) PMID:12586313
beta 1,2 and 3-adrenergic receptors in cattle were positively associated with hepatic activities of gluconeogenetic enzymes and with plasma glucose levels, suggesting functional importance PMID:15760672

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Subcellular Location

Cell membrane; Multi-pass membrane protein. Early endosome. Golgi apparatus.

Protein Families

G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB2 sub-subfamily

Tissue Specificity

Expressed in oviduct epithelial cells with high levels during the luteal phase of the sexual cycle. Lower levels around ovulation. Also expressed in liver.

Database Links

UNIGENE: Bt.100

KEGG: bta:281605

STRING: 9913.ENSBTAP00000002779

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