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Recombinant Arabidopsis thaliana Mitochondrial outer membrane protein porin 3 (VDAC3)

Recombinant Arabidopsis thaliana Mitochondrial outer membrane protein porin 3 (VDAC3)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

VDAC3

Purity

>85% (SDS-PAGE)

Target Names

VDAC3

Uniprot NO.

Q9SMX3

Species

Arabidopsis thaliana (Mouse-ear cress)

Source

Yeast

Expression Region

2-274

Target Protein Sequence

VKGPGLYTE IGKKARDLLY RDYQGDQKFS VTTYSSTGVA ITTTGTNKGS LFLGDVATQV KNNNFTADVK VSTDSSLLTT LTFDEPAPGL KVIVQAKLPD HKSGKAEVQY FHDYAGISTS VGFTATPIVN FSGVVGTNGL SLGTDVAYNT ESGNFKHFNA GFNFTKDDLT ASLILNDKGE KLNASYYQIV SPSTVVGAEI SHNFTTKENA ITVGTQHALD PLTTVKARVN NAGVANALIQ HEWRPKSFFT VSGEVDSKAI DKSAKVGIAL ALKP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.

Gene References into Functions

VDAC3 has a large conductance and is open at or around 0 mV and closes at positive or negative voltages.VDAC3 exhibits both fast and slow kinetics. PMID:25686492
Alternative cleavage and polyadenylation produces two major isoforms of VDAC3; the longest mRNA is targeted to the mitochondrial surface PMID:24889622
AtVDAC3 is in abundance in plasma membrane. PMID:22294207
VDAC3 expression is low compared with other VDAC members and its knockout mutant does not show any clear phenotype. PMID:21705391
The plant-specific kinesin, KP1, specifically interacts with VDAC3 on the mitochondrial outer membrane and that both KP1 and VDAC3 regulate aerobic respiration during seed germination at low temperature. PMID:21406623