Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Value-added Deliverables
① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive;
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.
Gene References into Functions
VDAC3 has a large conductance and is open at or around 0 mV and closes at positive or negative voltages.VDAC3 exhibits both fast and slow kinetics.PMID:25686492
Alternative cleavage and polyadenylation produces two major isoforms of VDAC3; the longest mRNA is targeted to the mitochondrial surfacePMID:24889622
AtVDAC3 is in abundance in plasma membrane.PMID:22294207
VDAC3 expression is low compared with other VDAC members and its knockout mutant does not show any clear phenotype.PMID:21705391
The plant-specific kinesin, KP1, specifically interacts with VDAC3 on the mitochondrial outer membrane and that both KP1 and VDAC3 regulate aerobic respiration during seed germination at low temperature.PMID:21406623
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Subcellular Location
Cell membrane. Mitochondrion outer membrane.
Protein Families
Eukaryotic mitochondrial porin (TC 1.B.8.1) family