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Recombinant Arabidopsis thaliana Heat shock 70 kDa protein 11 (HSP70-11), partial

Recombinant Arabidopsis thaliana Heat shock 70 kDa protein 11 (HSP70-11), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

HSP70-11

Purity

>85% (SDS-PAGE)

Target Names

MED37A

Uniprot NO.

Q9LKR3

Alternative Names

BIP1; HSP70-11; MED37_5; MED37A; At5g28540; T26D3.10; T26D3_50Heat shock 70 kDa protein BIP1; Heat shock 70 kDa protein 11; Heat shock protein 70-11; AtHsp70-11; Luminal-binding protein 1; AtBP1; BiP1

Species

Arabidopsis thaliana (Mouse-ear cress)

Source

Yeast

Expression Region

28-669

Target Protein Sequence

IEE ATKLGSVIGI DLGTTYSCVG VYKNGHVEII ANDQGNRITP SWVGFTDSER LIGEAAKNQA AVNPERTVFD VKRLIGRKFE DKEVQKDRKL VPYQIVNKDG KPYIQVKIKD GETKVFSPEE ISAMILTKMK ETAEAYLGKK IKDAVVTVPA YFNDAQRQAT KDAGVIAGLN VARIINEPTA AAIAYGLDKK GGEKNILVFD LGGGTFDVSV LTIDNGVFEV LSTNGDTHLG GEDFDHRVME YFIKLIKKKH QKDISKDNKA LGKLRRECER AKRALSSQHQ VRVEIESLFD GVDFSEPLTR ARFEELNNDL FRKTMGPVKK AMDDAGLQKS QIDEIVLVGG STRIPKVQQL LKDFFEGKEP NKGVNPDEAV AYGAAVQGGI LSGEGGDETK DILLLDVAPL TLGIETVGGV MTKLIPRNTV IPTKKSQVFT TYQDQQTTVS IQVFEGERSL TKDCRLLGKF DLNGIPPAPR GTPQIEVTFE VDANGILNVK AEDKASGKSE KITITNEKGR LSQEEIDRMV KEAEEFAEED KKVKEKIDAR NALETYVYNM KNQVNDKDKL ADKLEGDEKE KIEAATKEAL EWLDENQNSE KEEYDEKLKE VEAVCNPIIT AVYQRSGGAP GGAGGESSTE EEDESHDEL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions. Involved in polar nuclei fusion during female gametophyte development and is essential for the regulation of endosperm nuclei proliferation. Involved in sperm nuclear fusion with central cell polar nuclei at fertilization, which is critical for normal endosperm nuclear proliferation. Required for pollen development and pollen tube growth. Possesses ATPase activity in vitro.

Gene References into Functions

BIP3 supports the early stages of female gametophyte development, but not polar nuclear fusion, in the absence of BiP1 and BiP2. PMID:26251880
the bip1 bip2 bip3 triple mutation is lethal in pollen. PMID:24486762
bip1 bip2 double mutation causes defects in the fusion of polar nuclei during female gametophyte development. PMID:20080634

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Subcellular Location

Endoplasmic reticulum lumen. Nucleus.

Protein Families

Heat shock protein 70 (TC 1.A.33) family, DnaK subfamily

Tissue Specificity

Expressed in mature pollen grains, and pollen tubes.

Database Links

UNIGENE: At.23381

KEGG: ath:AT5G28540

STRING: 3702.AT5G28540.1

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