MED37A Antibody, FITC conjugated

Code: CSB-PA888748LC01DOA

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Size:

50μl100μl

US$166

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Species Reactivity: Arabidopsis thaliana

Raised in: Rabbit

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Target Background

Product Details

Uniprot NO.

Q9LKR3

Target Names

MED37A

Alternative Names

BIP1 antibody; HSP70-11 antibody; MED37_5 antibody; MED37A antibody; At5g28540 antibody; T26D3.10 antibody; T26D3_50Heat shock 70 kDa protein BIP1 antibody; Heat shock 70 kDa protein 11 antibody; Heat shock protein 70-11 antibody; AtHsp70-11 antibody; Luminal-binding protein 1 antibody; AtBP1 antibody; BiP1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana Mediator of RNA polymerase II transcription subunit 37a protein (28-669AA)

Immunogen Species

Arabidopsis thaliana

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-4 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function(From Uniprot)

In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions. Involved in polar nuclei fusion during female gametophyte development and is essential for the regulation of endosperm nuclei proliferation. Involved in sperm nuclear fusion with central cell polar nuclei at fertilization, which is critical for normal endosperm nuclear proliferation. Required for pollen development and pollen tube growth. Possesses ATPase activity in vitro.

Gene References into Functions

BIP3 supports the early stages of female gametophyte development, but not polar nuclear fusion, in the absence of BiP1 and BiP2. PMID:26251880
the bip1 bip2 bip3 triple mutation is lethal in pollen. PMID:24486762
bip1 bip2 double mutation causes defects in the fusion of polar nuclei during female gametophyte development. PMID:20080634

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Subcellular Location

Endoplasmic reticulum lumen. Nucleus.

Protein Families

Heat shock protein 70 (TC 1.A.33) family, DnaK subfamily

Tissue Specificity

Expressed in mature pollen grains, and pollen tubes.

Database Links

UNIGENE: At.23381

KEGG: ath:AT5G28540

STRING: 3702.AT5G28540.1

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