TAS2R3 Antibody

Code: CSB-PA020239

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Size:

50μg100μg

US$119

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Species Reactivity: Human

Raised in: Rabbit

Application: IF, ELISA

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Target Background

Product Details

Uniprot NO.

Q9NYW6

Target Names

TAS2R3

Alternative Names

TAS2R3; Taste receptor type 2 member 3; T2R3

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of Human T2R3.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Tested Applications

IF, ELISA

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.

Gene References into Functions

differences in the bitterness from chemicals associated with genetic polymorphisms in bitter taste receptor genes, specifically in TAS2R3, -4, -5 as well as TAS2R38. PMID:26785164
Our results show that the expression rate of some of the T2R taste receptor genes was increased significantly in patients with phantogeusia. PMID:22397221
Includes the study of a polymorphic upstream ORF in this gene, and shows that it functions to reduce protein levels by ~58%. PMID:19372376

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Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor T2R family

Tissue Specificity

Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. Expressed in the antrum and fundus (part of the stomach), duodenum and in gastric endocrine cells.

Database Links

HGNC: 14910

UNIGENE: Hs.676011

KEGG: hsa:50831

STRING: 9606.ENSP00000247879

OMIM: 604868

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