Serpina1 Antibody

Code: CSB-PA021053HA01RA

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Size:

20μg50μg100μg

US$83

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Species Reactivity: Rat

Raised in: Rabbit

Application: ELISA

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Target Background

Product Details

Uniprot NO.

P17475

Target Names

Serpina1

Alternative Names

Serpina1Alpha-1-antiproteinase antibody; Alpha-1-antitrypsin antibody; Alpha-1-proteinase inhibitor antibody; Serpin A1 antibody

Raised in

Rabbit

Species Reactivity

Rat

Immunogen

Recombinant Rat Alpha-1-antiproteinase protein (25-411AA)

Immunogen Species

Rattus norvegicus (Rat)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Tested Applications

ELISA

Protocols

ELISA Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Inhibitor of serine proteases. The primary target is elastase, but also has a moderate affinity for plasmin and thrombin.

Gene References into Functions

A1AT bidirectional uptake and secretion from lung endothelial cells towards the alveolar epithelium and airspaces PMID:24743137
These results suggest that transfer of the N-terminal acidic extension of HCII to alpha1-PI M358R enhanced its inhibition of thrombin by conferring the ability to bind exosite 1 on HAPI M358R. PMID:16981704

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Subcellular Location

Secreted.

Protein Families

Serpin family

Tissue Specificity

Plasma.

Database Links

UNIGENE: Rn.1419

KEGG: rno:24648

STRING: 10116.ENSRNOP00000012577

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