PDZD3 Antibody

Code: CSB-PA774807LA01HU

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20μg50μg100μg

US$83

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Species Reactivity: Human, Mouse

Raised in: Rabbit

Application: ELISA, WB, IHC

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Product Details
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Target Background

Product Details

Uniprot NO.

Q86UT5

Target Names

PDZD3

Alternative Names

IKEPP antibody; Intestinal and kidney enriched PDZ protein antibody; Intestinal and kidney-enriched PDZ protein antibody; Na(+)/H(+) exchange regulatory cofactor NHE-RF4 antibody; Na/Pi cotransporter C terminal associated protein 2 antibody; Na/Pi cotransporter C-terminal-associated protein 2 antibody; NaPi-Cap2 antibody; Natrium-phosphate cotransporter IIa C-terminal-associated protein 2 antibody; NHERF-4 antibody; NHERF4 antibody; NHRF4_HUMAN antibody; PDZ domain containing 2 antibody; PDZ domain containing 3 antibody; PDZ domain containing protein 2 antibody; PDZ domain-containing protein 2 antibody; PDZ domain-containing protein 3 antibody; PDZD 3 antibody; Pdzd3 antibody; PDZK2 antibody; Protein DLNB27 antibody; Sodium-hydrogen exchanger regulatory factor 4 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Na(+)/H(+) exchange regulatory cofactor NHE-RF4 protein (42-291AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Western blot
All lanes: PDZD3 antibody at 2µg/ml
Lane 1: Mouse kidney tissue
Lane 2: Mouse heart tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 62, 55, 53, 42, 25 kDa
Observed band size: 62 kDa
Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA774807LA01HU at dilution of 1:100

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Target Background

Function(From Uniprot)

Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions.

Gene References into Functions

The NHERF4 is a novel modulator of luminal fluidity in the intestine by adjusting SLC26A3 expression and activity through a phosphorylation-dependent mechanism. PMID:22627094
IKEPP was also found to be expressed in vascular endothelial cells where it co-localizes and complexes with the hIP PMID:22884631
A novel PDZ protein regulates the activity of guanylyl cyclase C, the heat-stable enterotoxin receptor. PMID:11950846
Regulation of NHE3 depends on the nature of the NHERF family member associating with NHE3 and the accompanying NHE3 complexes. PMID:19088451