LDHC Antibody

Code: CSB-PA012844LA01HU
Size:
20μg
20μg50μg100μg
US$83
Quantity:
Species Reactivity: Human, Mouse, Rat
Raised in: Rabbit
Application: ELISA, WB, IHC, IF
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Product Details

Uniprot NO.
Target Names
LDHC
Alternative Names
Cancer/testis antigen 32 antibody; CT32 antibody; EC 1.1.1.27 antibody; L lactate dehydrogenase C chain antibody; L-lactate dehydrogenase C chain antibody; Lactate Dehydrogenase C antibody; Lactate dehydrogenase c variant 1 antibody; Lactate dehydrogenase c variant 3 antibody; Lactate dehydrogenase c variant 4 antibody; Lactate dehydrogenase C4 antibody; LDH C antibody; LDH testis subunit antibody; LDH X antibody; LDH-C antibody; LDH-X antibody; LDH3 antibody; ldhc antibody; LDHC_HUMAN antibody; LDHX antibody; MGC111073 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Human L-lactate dehydrogenase C chain protein (2-332AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
ApplicationRecommended Dilution
WB1:500-1:5000
IHC1:20-1:200
IF1:50-1:200
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA
Images
  • Western Blot
    Positive WB detected in: NIH/3T3 whole cell lysate, HepG2 whole cell lysate, Mouse brain tissue, Mouse heart tissue, Mouse lung tissue, Mouse thymus tissue, Rat liver tissue
    All lanes: LDHC antibody at 3.2μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 37 kDa
    Observed band size: 37 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA012844LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA012844LA01HU at dilution of 1:100

  • Immunofluorescent analysis of Hela cells using CSB-PA012844LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Possible role in sperm motility.
Gene References into Functions
  1. Lactate dehydrogenase C may act as a novel biomarker for renal cell carcinoma progression and a potential therapeutic target for the treatment of renal cell carcinoma. PMID:28351304
  2. three uniquely identified proteins (CDK6 , galectin-3-binding protein and LDH C) were found, which show tight connection with prostate cancer and presence of all of them was previously linked to certain aspects of prostate cancer PMID:26503549
  3. Down-regulated LDH-C4 expression is significantly correlated with lowered enzyme activity in human spermatozoa. PMID:25795631
  4. This is the first report to show a positive correlation between LDH-3 and hemolytic parameters in sickle cell anemia. PMID:26069337
  5. LDH3 was increased in essential thrombocythemia. This isoenzymatic pattern could be expression of a metabolic adaptation. PMID:17178662
  6. LDH3 is a supporting diagnostic marker in cases of chronic tuberculosis. PMID:17935709
  7. hLdhc expression in cancer cells was regulated by transcription factor Sp1 and CREB and promoter CGI methylation PMID:18930904

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Subcellular Location
Cytoplasm.
Protein Families
LDH/MDH superfamily, LDH family
Database Links

HGNC: 6544

UNIGENE: Hs.654377

KEGG: hsa:3948

STRING: 9606.ENSP00000280704

OMIM: 150150

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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