H2AFB1 Antibody

Code: CSB-PA010091LA01HU
Size:
20μg
20μg50μg100μg
US$83
Quantity:
Species Reactivity: Human
Raised in: Rabbit
Application: ELISA, IHC, IF
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Product Details

Uniprot NO.
Target Names
H2AFB1
Alternative Names
H2AB1 antibody; H2AFB1 antibody; Histone H2A-Bbd type 1 antibody; H2A Barr body-deficient antibody; H2A.B antibody; H2A.Bbd antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Histone H2A-Bbd type 1 protein (1-115AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Tested Applications
ELISA, IHC, IF
Recommended Dilution
ApplicationRecommended Dilution
IHC1:20-1:200
IF1:50-1:200
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA
Images
  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA010091LA01HU at dilution of 1:100

  • Immunofluorescent analysis of MCF-7 cells using CSB-PA010091LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase. They associate with spliceosome components and are required for mRNA splicing.
Subcellular Location
Nucleus. Chromosome.
Protein Families
Histone H2A family
Tissue Specificity
Present in mature sperm.
Database Links

HGNC: 22516

UNIGENE: Hs.534498

KEGG: hsa:474382

STRING: 9606.ENSP00000346450

OMIM: 300445

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No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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