GPRC5C Antibody

CSB-PA030275

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Size:

50μg100μg

US$119

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Species Reactivity: Human,Mouse,Rat,Monkey

Raised in: Rabbit

Application: WB, IF, ELISA

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Product Details
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Target Background

Product Details

Uniprot NO.

Q9NQ84

Target Names

GPRC5C

Alternative Names

GPRC5C; RAIG3; PSEC0087; G-protein coupled receptor family C group 5 member C; Retinoic acid-induced gene 3 protein; RAIG-3

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat,Monkey

Immunogen

Synthesized peptide derived from the Internal region of Human GPRC5C.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Tested Applications

WB, IF, ELISA

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Protocols

Western Blotting(WB) Protocol Immunofluorescence (IF) Protocol ELISA Protocol

Datasheet & COA

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Description

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Target Background

Function

This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.

Gene References into Functions

Data suggest that agents (such as all-trans retinoic acid) that activate GPRC5C restore and/or maintain functional insulin-secreting cells; GPRC5C appears to play role in regulation of expression of genes controlling apoptosis, cell survival, and cell proliferation in insulin-secreting cells. PMID:28228611

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Subcellular Location

Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Localized in the plasma membrane and perinuclear vesicles.

Protein Families

G-protein coupled receptor 3 family

Tissue Specificity

Expression is highest in the periphery, particularly in the stomach, but also in the kidney, liver, pancreas, and prostate. In brain, levels of expression are generally lower than in the periphery, with the exception of cerebellum, spinal cord, and dorsal

Database Links

HGNC: 13309

UNIGENE: Hs.446438

KEGG: hsa:55890

STRING: 9606.ENSP00000376403

OMIM: 605949

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