GPR34 Antibody

CSB-PA002776
Size:
50μg
50μg100μg
US$119
Quantity:
Species Reactivity: Human,Mouse,Rat,Monkey
Raised in: Rabbit
Application: IF, ELISA
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Product Details

Uniprot NO.
Target Names
GPR34
Alternative Names
GPR34; Probable G-protein coupled receptor 34
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat,Monkey
Immunogen
Synthesized peptide derived from the Internal region of Human GPR34.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Tested Applications
IF, ELISA
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA
Images
  • Western Blot analysis of COS7 cells using GPR34 Polyclonal Antibody
Description

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function
Orphan receptor.
Gene References into Functions
  1. By monitoring fused FLAG-tag and conformation-sensitive native epitope during expression of GPR34 mutants, a tri-basic motif in the first intracellular loop was identified as key topogenic signal that dictates the orientation of transmembrane domain-1. PMID:27086875
  2. GPR34 knockdown impairs the proliferation and migration of HGC-27 gastric cancer cells in vitro and provides a potential implication for therapy of gastric cancer. PMID:25673461
  3. up-regulation of GPR34 expression in human gastric carcinoma may play a critical role in tumor progression and in determining patient prognosis PMID:23836308
  4. The present studies confirm that GPR34 is a cellular receptor for LysoPS, especially with a fatty acid at the sn-2 position. PMID:22343749
  5. these results are the first to identify a role for a GPR34 in lymphoma cell growth, provide insight into GPR34-mediated signaling, identify a genetically unique subset of MZLs that express high levels of GPR34. PMID:22966169
  6. data show that multiple translation initiation starts and alternative splicing contribute to the supragenomic diversification of GPR34 PMID:16338117

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Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 1 family
Tissue Specificity
Broadly expressed.
Database Links

HGNC: 4490

UNIGENE: Hs.495989

KEGG: hsa:2857

STRING: 9606.ENSP00000367378

OMIM: 300241

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