GNAZ Antibody, Biotin conjugated

Code: CSB-PA009601LD01HU

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Size:

50μg100μg

US$166

Quantity:

Species Reactivity: Human

Raised in: Rabbit

Application: ELISA

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Target Background

Product Details

Uniprot NO.

P19086

Target Names

GNAZ

Alternative Names

G(x) alpha chain antibody; GNAZ antibody; GNAZ_HUMAN antibody; Guanine nucleotide-binding protein G(z) subunit alpha antibody; Gz-alpha antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Guanine nucleotide-binding protein G(z) subunit alpha protein (3-140AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Tested Applications

ELISA

Protocols

ELISA Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

Gene References into Functions

GNAZ mutations are associated with melanoma. PMID:20424519
cGMP-phosphodiesterase 6 can be activated by another cancer-retina antigen, transducin, through Wnt5a-Frizzled-2 cascade, which leads to a lowering of cGMP and an increase in intracellular calcium mobilization. PMID:19946729
findings suggest that Galphaz signals may attenuate Rho-induced stimulation of SRF-mediated transcription PMID:15326221

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Subcellular Location

Membrane; Lipid-anchor.

Protein Families

G-alpha family, G(i/o/t/z) subfamily

Database Links

HGNC: 4395

UNIGENE: Hs.584760

KEGG: hsa:2781

STRING: 9606.ENSP00000248996

OMIM: 139160

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