GNAZ Antibody

CSB-PA002856

Rate （N/A）
Review （0）

Size:

50μg100μg

US$119

Quantity:

Species Reactivity: Human,Mouse,Rat,Monkey

Raised in: Rabbit

Application: WB, IHC, ELISA

Send an Inquiry

Start an on-line Chat

Orders can only be placed from within the U.S.

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Uniprot NO.

P19086

Target Names

GNAZ

Alternative Names

G(x) alpha chain antibody; GNAZ antibody; GNAZ_HUMAN antibody; Guanine nucleotide-binding protein G(z) subunit alpha antibody; Gz-alpha antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat,Monkey

Immunogen

Synthesized peptide derived from Human Gz-α around the non-phosphorylation site of S16.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Tested Applications

WB, IHC, ELISA

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Protocols

Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol ELISA Protocol

Datasheet & COA

Antibody FAQs

Images

Western Blot analysis of HuvEc cells using Gz-α Polyclonal Antibody

Description

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

Gene References into Functions

GNAZ mutations are associated with melanoma. PMID:20424519
cGMP-phosphodiesterase 6 can be activated by another cancer-retina antigen, transducin, through Wnt5a-Frizzled-2 cascade, which leads to a lowering of cGMP and an increase in intracellular calcium mobilization. PMID:19946729
findings suggest that Galphaz signals may attenuate Rho-induced stimulation of SRF-mediated transcription PMID:15326221

Hide All

Subcellular Location

Membrane; Lipid-anchor.

Protein Families

G-alpha family, G(i/o/t/z) subfamily

Database Links

HGNC: 4395

UNIGENE: Hs.584760

KEGG: hsa:2781

STRING: 9606.ENSP00000248996

OMIM: 139160

Promotions