GDF7 Antibody, FITC conjugated

Code: CSB-PA768769LC01HU

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Size:

50μg100μg

US$166

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Species Reactivity: Human

Raised in: Rabbit

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Target Background

Product Details

Uniprot NO.

Q7Z4P5

Target Names

GDF7

Alternative Names

bmp12 antibody; bone morphogenetic protein 12 antibody; GDF-7 antibody; Gdf7 antibody; GDF7_HUMAN antibody; growth differentiation factor 7 antibody; Growth/differentiation factor 7 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Growth/differentiation factor 7 protein (322-450AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

May play an active role in the motor area of the primate neocortex.

Gene References into Functions

BMP-12 activates tenogenic pathway in human adipose stem cells. PMID:28214472
The Barrett-associated variants at GDF7 and TBX5 also increase esophageal adenocarcinoma risk. PMID:26783083
closest protein-coding genes were respectively GDF7 (rs3072), which encodes a ligand in the bone morphogenetic protein pathway, and TBX5 (rs2701108), which encodes a transcription factor that regulates esophageal and cardiac development PMID:25447851
BMP12 induces tenogenic differentiation of adipose-derived stromal cells via the Smad1/5/8 pathway. PMID:24155967
studies show that even though tenogenic (BMP 12 and BMP 13) and osteogenic (BMP2) BMPs bind the same receptors with high affinity they signal much differently and result in differential activation of osteogenic and tenogenic markers PMID:21702718
induces ligamentogenic differentiation in mesenchymal progenitors PMID:20334610
stimulates expression of both chondrogenic and osteoblstic markers in pluripotent mesenchymal C3H10T1/2 cells. PMID:20102312
In mouse, the expression of Gdf7 in roof plate cells is required for the fidelity of commissural axon growth. PMID:12741987