ENOX1 Antibody, HRP conjugated

Code: CSB-PA007676LB01HU

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50μg100μg

US$166

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Species Reactivity: Human

Raised in: Rabbit

Application: ELISA

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Target Background

Product Details

Uniprot NO.

Q8TC92

Target Names

ENOX1

Alternative Names

ENOX1 antibody; PIG38Ecto-NOX disulfide-thiol exchanger 1 antibody; Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase antibody; cCNOX antibody; Cell proliferation-inducing gene 38 protein antibody; Constitutive Ecto-NOX antibody; cNOX) [Includes: Hydroquinone [NADH] oxidase antibody; EC 1.-.-.-); Protein disulfide-thiol oxidoreductase antibody; EC 1.-.-.-)] antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Ecto-NOX disulfide-thiol exchanger 1 protein (101-340AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Tested Applications

ELISA

Protocols

ELISA Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock.

Gene References into Functions

We verified that NRF-1 positively regulates FAM134C and ENOX1, and negatively regulates C3orf10 in human neuroblastoma IMR-32 cells and primary rat cortical neurons. PMID:23939472
These results indicate that this sequence variant in ENOX1 may contribute to the familial autoimmune myasthenia in these patients. PMID:22744667
copper-binding capacity, enzymatic activity, and time-keeping (clock) properties PMID:19055324

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Subcellular Location

Cell membrane. Secreted, extracellular space. Note=Extracellular and plasma membrane-associated.

Protein Families

ENOX family

Tissue Specificity

Expressed in lymphocyte cells, breast and breast cancer (at protein level). Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Found also in the serum of heal

Database Links

HGNC: 25474

UNIGENE: Hs.128258

KEGG: hsa:55068

STRING: 9606.ENSP00000261488

OMIM: 610914

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