ENOX1 Antibody

Code: CSB-PA007676LA01HU
Size:
20μg
20μg50μg100μg
US$83
Quantity:
Species Reactivity: Human
Raised in: Rabbit
Application: ELISA, WB, IHC
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Product Details

Uniprot NO.
Target Names
ENOX1
Alternative Names
ENOX1 antibody; PIG38Ecto-NOX disulfide-thiol exchanger 1 antibody; Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase antibody; cCNOX antibody; Cell proliferation-inducing gene 38 protein antibody; Constitutive Ecto-NOX antibody; cNOX) [Includes: Hydroquinone [NADH] oxidase antibody; EC 1.-.-.-); Protein disulfide-thiol oxidoreductase antibody; EC 1.-.-.-)] antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ecto-NOX disulfide-thiol exchanger 1 protein (101-340AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Tested Applications
ELISA, WB, IHC
Recommended Dilution
ApplicationRecommended Dilution
WB1:1000-1:5000
IHC1:20-1:200
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA
Images
  • Western blot
    All lanes: ENOX1 antibody at 5µg/ml
    Lane 1: Jurkat whole cell lysate
    Lane 2: Raji whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 74, 28 kDa
    Observed band size: 74 kDa

  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA007676LA01HU at dilution of 1:100

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock.
Gene References into Functions
  1. We verified that NRF-1 positively regulates FAM134C and ENOX1, and negatively regulates C3orf10 in human neuroblastoma IMR-32 cells and primary rat cortical neurons. PMID:23939472
  2. These results indicate that this sequence variant in ENOX1 may contribute to the familial autoimmune myasthenia in these patients. PMID:22744667
  3. copper-binding capacity, enzymatic activity, and time-keeping (clock) properties PMID:19055324

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Subcellular Location
Cell membrane. Secreted, extracellular space. Note=Extracellular and plasma membrane-associated.
Protein Families
ENOX family
Tissue Specificity
Expressed in lymphocyte cells, breast and breast cancer (at protein level). Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Found also in the serum of heal
Database Links

HGNC: 25474

UNIGENE: Hs.128258

KEGG: hsa:55068

STRING: 9606.ENSP00000261488

OMIM: 610914

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