Ccl12 Antibody

Code: CSB-PA09139A0Rb
Size:
20μg
20μg50μg100μg
US$83
Quantity:
Species Reactivity: Mouse
Raised in: Rabbit
Application: ELISA
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Product Details

Uniprot NO.
Target Names
Ccl12
Alternative Names
C-C motif chemokine 12 antibody; Ccl12 antibody; CCL12_MOUSE antibody; Macrophage/monocyte Chemotactic Protein antibody; MCP-1-related chemokine antibody; MCP-5 antibody; Monocyte chemoattractant protein 5 antibody; Monocyte chemotactic protein 5 antibody; OTTMUSP00000000792 antibody; Scya12 antibody; Small inducible cytokine A12 antibody; Small-inducible cytokine A12 antibody
Raised in
Rabbit
Species Reactivity
Mouse
Immunogen
Recombinant Mouse C-C motif chemokine 12 ptotein (23-104AA)
Immunogen Species
Mus musculus (Mouse)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Tested Applications
ELISA
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.
Gene References into Functions
  1. After 100% O2 treatment, genes involved in inflammation (Ccl12), angiogenesis (Igfr1, Stat3), and metabolism (Hk2) were upregulated. PMID:24458145
  2. Data indicate mRNA upregulation of CCR2 and CCR2 ligands CCL2, CCL7, CCL8, and CCL12 in aortas from DOCA/salt-treated hypertension. PMID:23033370
  3. The transforming growth factor (TGF)beta type II receptor/MCP-5 axis is an essential crossroad for joint development and endochondral growth. PMID:22814601
  4. CCL12 proteins were present in the vast majority of tissues investigated. mRNA for these proteins was also expressed in most of these tissues suggesting local production and the ability to respond in situ to inflammatory stimuli. PMID:20931267

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Subcellular Location
Secreted.
Protein Families
Intercrine beta (chemokine CC) family
Tissue Specificity
Predominantly expressed in the lymph nodes and thymus. Also found in the salivary glands containing lymph nodes, breast, heart, lung, brain, small intestine, kidney and colon.
Database Links

UNIGENE: Mm.867

KEGG: mmu:20293

STRING: 10090.ENSMUSP00000000194

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