CHRM5 Antibody

CSB-PA006813
Size:
50μg
50μg100μg
US$119
Quantity:
Species Reactivity: Human
Raised in: Rabbit
Application: WB, IF, ELISA
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Product Details

Uniprot NO.
Target Names
CHRM5
Alternative Names
CHRM5; Muscarinic acetylcholine receptor M5
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human mAChR M5.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Tested Applications
WB, IF, ELISA
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA
Images
  • Western Blot analysis of Jurkat cells using mAChR M5 Polyclonal Antibody
Description

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Gene References into Functions
  1. Immunological stimulation leads to M5 mAChR gene expression in lymphocytes. PMID:12675126
  2. direct evidence suggesting that the M5 muscarinic receptor gene combined with the alpha7-nicotinic receptor gene may be linked to schizophrenia PMID:15292665
  3. mAChR subtypes (m1 to m5)presents in human scleral fibroblasts at both mRNA and protein levels. PMID:16877267
  4. the first study to show an association between CHRM5 and substance use in humans PMID:17608938

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Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 1 family, Muscarinic acetylcholine receptor subfamily, CHRM5 sub-subfamily
Database Links

HGNC: 1954

UNIGENE: Hs.584747

KEGG: hsa:1133

STRING: 9606.ENSP00000372750

OMIM: 118496

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