CCL4 Antibody

Code: CSB-PA004797KA01HU

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Size:

100μl

US$398

Quantity:

Species Reactivity: Human,Mouse,Rat

Raised in: Rabbit

Application: ELISA,WB,IHC

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Target Background

Product Details

Uniprot NO.

P13236

Target Names

CCL4

Alternative Names

MIP 1 beta antibody; Secreted protein G 26 antibody; ACT 2 antibody; ACT-2 antibody; ACT2 antibody; AT744.1 antibody; AT744.2 antibody; C C motif chemokine 4 antibody; C C motif chemokine 4 like antibody; C C motif chemokine ligand 4 like 1 antibody; C C motif chemokine ligand 4 like 2 antibody; CC chemokine ligand 4 antibody; CC chemokine ligand 4L1 antibody; CC chemokine ligand 4L1d2 antibody; CC chemokine ligand 4L2 antibody; CCL4 antibody; CCL4_HUMAN antibody; ccl4l 1 antibody; CCL4L antibody; CCL4L1 antibody; Chemokine (C C motif) ligand 4 antibody; Chemokine (C C motif) ligand 4 like 1 antibody; Chemokine (C C motif) ligand 4 like 1; telomeric antibody; Chemokine (C C motif) ligand 4 like 2 antibody; Chemokine CC Motif Ligand 4 antibody; G 26 antibody; G 26 T lymphocyte secreted protein antibody; G-26 T-lymphocyte-secreted protein antibody; HC21 antibody; Immune activation 2 antibody; LAG 1 antibody; LAG-1 antibody; LAG1 antibody; Lymphocyte activation gene 1 antibody; Lymphocyte activation gene 1 protein antibody; Macrophage inflammatory protein 1 beta antibody; Macrophage inflammatory protein 1-beta antibody; Macrophage inflammatory protein 1b2 antibody; MGC104418 antibody; MGC126025 antibody; MGC126026 antibody; MIP-1-beta antibody; MIP-1-beta(1-69) antibody; MIP-1-beta(3-69) antibody; MIP1 beta antibody; MIP1B antibody; MIP1B1 antibody; Monocyte adherence induced protein 5 alpha antibody; PAT 744 antibody; Protein H400 antibody; SCYA2 antibody; SCYA4 antibody; SCYA4L antibody; SCYA4L1 antibody; SCYA4L2 antibody; SCYQ4L2 antibody; Secreted protein G 26 antibody; Secreted protein G26 antibody; SIS gamma antibody; SIS-gamma antibody; Small inducible cytokine A4 (homologous to mouse Mip 1b) antibody; Small inducible cytokine A4 antibody; small inducible cytokine A4-like antibody; Small-inducible cytokine A4 antibody; T cell activation protein 2 antibody; T-cell activation protein 2 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

A synthetic peptide of Human CCL4

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH7.3.

Tested Applications

ELISA,WB,IHC

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Western blot analysis of extracts of SGC7901 cell lines, using CCL4 antibody.

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Target Background

Function(From Uniprot)

Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.

Gene References into Functions

identified 13 ADCC-activated genes. Six gene expression assays including 8 of the 13 genes (CCL3, CCL4/CCL4L1/CCL4L2, CD160, IFNG, NR4A3 and XCL1/XCL2) were analyzed in 127 kidney biopsies PMID:25449536
PCR results show that lower copy numbers of CCL4L1 are observed in the Caucasian population nd higher copy numbers are observed in the Black population of South Africa. PMID:24727646
CCL4L1 allele frequency is higher in severe psoriasis, whereas CCL4L2 is more frequent in patients with a milder disease. PMID:21614014
multiple copies of CCL3L1 and CCL4L1 present in a single diploid genome are the result of segmental duplication at chromosome 17q12 PMID:15028295