C1QTNF1 Antibody

Code: CSB-PA871599EA01HU

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20μg50μg100μg

US$83

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Species Reactivity: Human

Raised in: Rabbit

Application: ELISA, IHC

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Target Background

Product Details

Uniprot NO.

Q9BXJ1

Target Names

C1QTNF1

Alternative Names

C1q and tumor necrosis factor related protein 1 antibody; C1QT1_HUMAN antibody; C1QTNF1 antibody; Complement C1q tumor necrosis factor related protein 1 antibody; Complement C1q tumor necrosis factor-related protein 1 antibody; CTRP 1 antibody; CTRP1 antibody; FLJ90694 antibody; G protein coupled receptor interacting protein 1 antibody; G protein-coupled receptor-interacting protein antibody; GIP antibody; ZSIG37 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Complement C1q tumor necrosis factor-related protein 1 protein (26-281AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA871599EA01HU at dilution of 1:100

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Target Background

Gene References into Functions

CTRP1 has a role in linking dysregulation of lipid metabolism and inflammatory responses in macrophages PMID:27175610
High serum CTRP1 level is associated with Type 2 diabetes mellitus. PMID:28207876
In cultured endothelial cells, treatment of CTRP1 led to increased permeability to fluorescent-labelled dextran and apparent formation of paracellular holes as observed after disturbed flow exposure, which was evidently reduced in the presence of a CTRP1-specific neutralizing antibody. PMID:28625919
Increased serum CTRP 1 levels were closely associated with the prevalence and severity of CAD, it might be regarded as a marker for myocardial infarction. PMID:27169633
the strong association of CTRP1 with insulin resistance in NAFLD PMID:25767880
The levels of circulating CTRP1 are associated with coronary artery disease in men. PMID:24945145
The variation of plasma CTRP-1 and IL-6 concentrations may play an important role in reflecting the degree of inflammation in CHD and the severity of coronary arterial atherosclerosis. PMID:25635749
Increased plasma CTRP1 was independently associated with type 2 diabetes. Profiling of plasma adipokines such as CTRP1 is particularly important to obtain a greater understanding of their contribution to the type 2 diabetic state. PMID:24965225
CTRP1 is a novel adipokine associated with type 2 diabetes mellitus in humans. PMID:24827430
CTRP1 level was significantly higher in subjects with metabolic syndrome compared to healthy subjects. PMID:23000311
The review describes the potential role of C1qTNF1 as an intracellular regulator of signal transduction PMID:16386877
molecular cloning, gene expression, and subcellular localization of GIP PMID:12409230
These findings indicate that CTRP1 expression may be associated with a low-grade chronic inflammation status in adipose tissues. PMID:16806199
CTRP1 enhances the production of aldosterone. CTRP1 was highly expressed in obese subjects as well as up-regulated in hypertensive patients, CTRP1 may be a newly identified molecular link between obesity and hypertension. PMID:18171693
CTRP1 may be considered a novel adipokine, providing an important framework to further address the physiological functions and mechanisms of the action of this family of secreted glycoproteins in normal and disease states. PMID:18783346