BIRC8 Antibody

Code: CSB-PA846680ESR2HU

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Size:

20μl50μl100μl

US$83

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Species Reactivity: Human

Raised in: Rabbit

Application: ELISA

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Target Background

Product Details

Uniprot NO.

Q96P09

Target Names

BIRC8

Alternative Names

Baculoviral IAP repeat containing 8 antibody; Baculoviral IAP repeat containing protein 8 antibody; Baculoviral IAP repeat-containing protein 8 antibody; BIRC 8 antibody; BIRC8 antibody; BIRC8 protein antibody; BIRC8_HUMAN antibody; hILP 2 antibody; hILP2 antibody; IAP like protein 2 antibody; IAP-like protein 2 antibody; ILP 2 antibody; ILP-2 antibody; Inhibitor of apoptosis like protein 2 antibody; Inhibitor of apoptosis-like protein 2 antibody; Testis specific inhibitor of apoptosis antibody; Testis-specific inhibitor of apoptosis antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Baculoviral IAP repeat-containing protein 8 protein (1-236AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Tested Applications

ELISA

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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BIRC8 Antibody

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Target Background

Function(From Uniprot)

Protects against apoptosis mediated by BAX.

Gene References into Functions

High ILP-2 expression is associated with breast cancer. PMID:30106449
Fumonisin B1 caused dose-dependent increase in BIRC-8/ILP-2 mRNA and protein expression in HepG2 cells to inhibit apoptosis. PMID:25800559
results indicate that ILP-2 is a novel breast cancer biomarker in the peripheral blood. PMID:23222679
increased expression with progression of chronic myeloid leukaemia PMID:24266799
role in preventing shear-stress induced endothelial cell apoptosis via negative regulation of caspase-3 PMID:12372615
ILP2 is an unstable protein, and cannot inhibit caspase 9 in a physiological way on its own; possibly ILP2 requires assistance from unidentified cellular factors to be an effective inhibitor of apoptosis in vivo PMID:15485395