BIRC8 Antibody

Code: CSB-PA002709GA01HU
Size:
100μl
100μl
US$600
Quantity:
Species Reactivity: Human,Mouse
Raised in: Rabbit
Application: ELISA,WB
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Product Details

Uniprot NO.
Target Names
BIRC8
Alternative Names
Baculoviral IAP repeat containing 8 antibody; Baculoviral IAP repeat containing protein 8 antibody; Baculoviral IAP repeat-containing protein 8 antibody; BIRC 8 antibody; BIRC8 antibody; BIRC8 protein antibody; BIRC8_HUMAN antibody; hILP 2 antibody; hILP2 antibody; IAP like protein 2 antibody; IAP-like protein 2 antibody; ILP 2 antibody; ILP-2 antibody; Inhibitor of apoptosis like protein 2 antibody; Inhibitor of apoptosis-like protein 2 antibody; Testis specific inhibitor of apoptosis antibody; Testis-specific inhibitor of apoptosis antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Human BIRC8
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Protects against apoptosis mediated by BAX.
Gene References into Functions
  1. High ILP-2 expression is associated with breast cancer. PMID:30106449
  2. Fumonisin B1 caused dose-dependent increase in BIRC-8/ILP-2 mRNA and protein expression in HepG2 cells to inhibit apoptosis. PMID:25800559
  3. results indicate that ILP-2 is a novel breast cancer biomarker in the peripheral blood. PMID:23222679
  4. increased expression with progression of chronic myeloid leukaemia PMID:24266799
  5. role in preventing shear-stress induced endothelial cell apoptosis via negative regulation of caspase-3 PMID:12372615
  6. ILP2 is an unstable protein, and cannot inhibit caspase 9 in a physiological way on its own; possibly ILP2 requires assistance from unidentified cellular factors to be an effective inhibitor of apoptosis in vivo PMID:15485395

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Subcellular Location
Cytoplasm.
Protein Families
IAP family
Tissue Specificity
Testis specific in normal tissues.
Database Links

HGNC: 14878

UNIGENE: Hs.348263

KEGG: hsa:112401

STRING: 9606.ENSP00000412957

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No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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