ADGRE1 Antibody

Code: CSB-PA613493ESR2HU

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Size:

20μl50μl100μl

US$83

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Species Reactivity: Human

Raised in: Rabbit

Application: ELISA, IHC

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Target Background

Product Details

Uniprot NO.

Q14246

Target Names

ADGRE1

Alternative Names

ADGRE1 antibody; Adhesion G protein coupled receptor E1 antibody; Adhesion G protein-coupled receptor E1 antibody; AGRE1_HUMAN antibody; Cell surface glycoprotein EMR1 antibody; Cell surface glycoprotein F4/80 antibody; DD7A5 7 antibody; Egf like module containing mucin like hormone receptor like 1 antibody; Egf like module containing mucin like hormone receptor like sequence 1 antibody; EGF like module receptor 1 antibody; EGF TM7 antibody; EGF-like module receptor 1 antibody; EGF-like module-containing mucin-like hormone receptor-like 1 antibody; EGFTM7 antibody; EMR 1 antibody; EMR1 antibody; EMR1 hormone receptor antibody; Gpf480 antibody; Ly71 antibody; Lymphocyte antigen 71 antibody; TM7LN3 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Adhesion G protein-coupled receptor E1 protein (21-290AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA613493ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA 613493ESR2HU at dilution of 1:100

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Citations

In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy J Li,/,2023

Target Background

Function(From Uniprot)

Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development.

Gene References into Functions

EMR1 expression is significantly upregulated in human masticatory mucosa during wound healing PMID:28005267
Additional transcription changes likely associated with Th2-like eosinophilic inflammation were prominent and included increased EMR1&3. PMID:20625511
Highly specific marker for eosinophils. PMID:17823986

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Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily

Tissue Specificity

Expression is restricted to eosinophils.

Database Links

HGNC: 3336

UNIGENE: Hs.2375

KEGG: hsa:2015

STRING: 9606.ENSP00000311545