Mouse lymphotactin,Lptn/LTN ELISA Kit

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Code: CSB-E08714m
Size:
96T,5×96T,10×96T
96T,5×96T,10×96T
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Quantity:
Sample Types: serum, plasma, tissue homogenates
Detect Range: 0.156 ng/ml - 10 ng/ml
Sensitivity: 0.039 ng/ml
Trial Size:
24T ELISA Kit Trial Size (Only USD$150/ kit)
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Product Details

Alternative Names
Xcl1 ELISA Kit; Lptn ELISA Kit; Ltn ELISA Kit; Scyc1 ELISA Kit; Lymphotactin ELISA Kit; C motif chemokine 1 ELISA Kit; Cytokine SCM-1 ELISA Kit; Lymphotaxin ELISA Kit; Small-inducible cytokine C1 ELISA Kit
Abbreviation
XCL1
Uniprot NO.
Species
Mus musculus (Mouse)
Sample Type
serum, plasma, tissue homogenates
Detection Range
0.156 ng/ml - 10 ng/ml
Sensitivity
0.039 ng/ml
Assay Time
1-5h
Sample Loading Volume
50-100ul
Detection Wavelength
450 nm
Research Area
Immunology
Assay Principle
quantitative
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Measurement
Sandwich
Storage
Store at 2-8°C. Please refer to protocol.
Shelf Life
6 months
Lead Time
3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Troubleshooting and FAQs
Description

This Mouse XCL1 ELISA Kit was designed for the quantitative measurement of Mouse XCL1 protein in serum, plasma, tissue homogenates. It is a Sandwich ELISA kit, its detection range is 0.156 ng/ml - 10 ng/ml and the sensitivity is 0.039 ng/ml.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
Gene References into Functions
  1. study provides in vitro and in vivo evidence that the interaction between XCL1 and alpha9 integrin has an important role for autoimmune diseases PMID:28550205
  2. The interaction between XCL1 and XCR1 plays a crucial role in the classical immunology response. PMID:27387353
  3. Data show that mice lacking either XCL1 or XCR1 exhibit similar specific defects in intestinal T cell populations as XCR1-dendritic cells (DC)-deficient mice. Therefore it is possible that the XCR1-XCL1 axis itself is directly involved in intestinal T cell homeostasis, via a mechanism that might either involve interaction with XCR1+ DCs or be independent of this pathway. PMID:27005831
  4. T inflammatory memory CD8 T cells participate to antiviral response and generate secondary memory cells with an advantage in XCL1 production PMID:22528127
  5. XCL1-mediated accumulation of dendritic cells in the thymic medulla contributes to naturally occurring regulatory T cell development and is regulated by Aire. PMID:21300913
  6. Data report the identification of a new stable molecular assembly formed between the ATAC and Mediator complexes in mouse embryonic stem cells. PMID:20508642
  7. The expression patterns of XCR1 and XCL1 were conserved in human and mice blood cells, including certain dendritic cell subsets. PMID:20541533
  8. MIP-1alpha, MIP-1beta, RANTES, and ATAC/lymphotactin function together with IFN-gamma as type 1 cytokines. PMID:11972057
  9. Adenovirus-mediated intratumoral Lptn gene transfer potentiates the antibody-targeted superantigen therapy of experimental melanoma. PMID:12226740
  10. In a brain-targeted HIV-1 Tat transgenic model, Tat expression up-regulates XCL1 production not only in Tat-expressing murine astrocytes, but also in monocytes and macrophages/microglia. PMID:14734774
  11. Lymphotactin gene-modified dendritoma induces T-cell proliferation and strong cytotoxic T lymphocytes reaction against allogenic hepatocellular carcinoma cells. PMID:17990361
  12. Results describe the role of XCL1 during the course of the immune response to pulmonary M. tuberculosis infection. PMID:19097989

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Subcellular Location
Secreted.
Protein Families
Intercrine gamma family
Tissue Specificity
Expressed in activated CD8(+) T cells. In the thymus, expressed by medullary thymic epithelial cells.
Database Links

UNIGENE: Mm.190

KEGG: mmu:16963

STRING: 10090.ENSMUSP00000027860

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