Mouse beta cellulin,BTC ELISA Kit

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Code: CSB-E07307m

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Size:

96T,5×96T,10×96T

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Quantity:

Sample Types: serum, plasma,tissue homogenates

Detect Range: 62.5 pg/ml -4000 pg/ml

Sensitivity: 15.6 pg/ml

Trial Size:

24T ELISA Kit Trial Size (Only USD$150/ kit)
* Sample kit cost can be deducted as a $30 credit for each 96-assay kit of the same analyte and brand you subsequently purchase within six months until depleted. More details >>

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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Alternative Names

Btc ELISA kit; BcnProbetacellulin [Cleaved into: Betacellulin ELISA kit; BTC)] ELISA kit

Abbreviation

BTC

Uniprot NO.

Q05928

Species

Mus musculus (Mouse)

Sample Type

serum, plasma,tissue homogenates

Detection Range

62.5 pg/ml -4000 pg/ml

Sensitivity

15.6 pg/ml

Assay Time

1-5h

Sample Loading Volume

50-100ul

Detection Wavelength

450 nm

Research Area

Signal Transduction

Assay Principle

quantitative
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Measurement

Sandwich

Storage

Store at 2-8°C. Please refer to protocol.

Shelf Life

6 months

Lead Time

3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Troubleshooting and FAQs

ELISA kit FAQs

ELISA Data Analysis

ELISA Standard Curve & Curve Expert software

Customer Reviews and Q&A

■ Customer Reviews

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Citations

Role of activin a hormone, betacellulin (BTC) growth factor, and Heparin binding epidermal growth factor on mice embryonic development after oral administration of glycyrrhiza glabra LA Fadhil,/,2022

Target Background

Function(From Uniprot)

Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.

Gene References into Functions

Betacellulin promotes the proliferation of corneal epithelial stem cells through the phosphorylation of Erk1/Erk2. PMID:29331377
The results of this study suggested a novel regulatory role of Btc in axon-Schwann cell interactions involved in myelin formation and nerve repair. PMID:28139851
BTC induces expansion of neural stem cells and neuroblasts, and promotes neurogenesis in the olfactory bulb and dentate gyrus. PMID:22232668
Betacellulin exerts proliferative activity on beta cells through the activation of ErbB-1 and ErbB-2 receptors PMID:21897861
BTC overexpression enhances glucose-induced insulin secretion in Mesenchyma Stem Cells PMID:20836700
Betacellulin protects from pancreatitis by activating stress-activated protein kinase. PMID:20038432
Excess of betacellulin exerts no deleterious effects on the structure or function of the male reproductive tract in mice. PMID:19931240
structure of the BTC gene PMID:12031500
Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling. PMID:12773386
Mice overexpressing BTC exhibit high early postnatal mortality, reduced body weight gain, impaired longitudinal growth, cataract, retinal and bone abnormalities, and lung disease. PMID:16179416
identified hitherto unknown effects of betacellulin (BTC) overabundance in reproduction and suggests BTC as a novel candidate protein for the modulation of fertility. PMID:17914071
role of BTC in the regulation of epidermal homeostasis, hair follicle morphogenesis and cycling, and wound angiogenesis PMID:17960175
Overexpression of BTC results in an EGFR-dependent upregulation of cortical bone mass in the appendicular skeleton of mice. PMID:19049329
Long-term BTC overabundance does not alter pancreatic islet structure and beta-cell mass, but enhances glucose-induced insulin secretion in vivo as well as in vitro. PMID:19100309
Reversal of streptozotocin-induced hyperglycemia by continouous supply of Btc. PMID:19378417

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Subcellular Location

[Betacellulin]: Secreted, extracellular space.; [Probetacellulin]: Cell membrane; Single-pass type I membrane protein.

Tissue Specificity

Found in several mouse tissues including kidney, uterus and liver, as well as in beta tumor cell line and MCF-7 cells. It is not detected in the brain.

Database Links

UNIGENE: Mm.2024

KEGG: mmu:12223

STRING: 10090.ENSMUSP00000112765

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