MSK1 Antibody

Code: CSB-PA329134XA01SVG

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

P32048

Target Names

MSK1

Alternative Names

MSK1 antibody; YNL073W antibody; N2364 antibody; Lysine--tRNA ligase antibody; mitochondrial antibody; EC 6.1.1.6 antibody; Lysyl-tRNA synthetase antibody; LysRS antibody

Raised in

Rabbit

Species Reactivity

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Immunogen

Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) MSK1 protein

Immunogen Species

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Gene References into Functions

one out of two cytosolic lysine tRNAs of the yeast Saccharomyces cerevisiae is partially internalized by mitochondria. The key protein factor of this process is the precursor of mitochondrial lysyl-tRNA synthetase, preMsk1p. PMID:27908233
In this work, the authors identify the hinge region with two adjacent helices H5 and H7 of preMSK1 to be responsible for mitochondrial targeting of the tRNA(Lys) and characterize preMsk1p versions with altered tRK1 import capacities. PMID:20064631

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Subcellular Location

Mitochondrion matrix.

Protein Families

Class-II aminoacyl-tRNA synthetase family

Database Links

KEGG: sce:YNL073W

STRING: 4932.YNL073W

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