sox2 Antibody

Code: CSB-PA761266XA01DIL

Rate （N/A）
Review （0）

Size:

0.1ml

0.1ml1ml

US$Enquire

Quantity:

Species Reactivity: Danio rerio (Zebrafish) (Brachydanio rerio)

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

Send an Inquiry

Start an on-line Chat

Online ordering is currently available for U.S. customers only. For orders outside the U.S., please kindly submit an inquiry or start a chat with us.

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Uniprot NO.

Q6P0E1

Target Names

sox2

Alternative Names

sox2 antibody; zgc:65860 antibody; zgc:77389 antibody; Transcription factor Sox-2 antibody

Raised in

Rabbit

Species Reactivity

Danio rerio (Zebrafish) (Brachydanio rerio)

Immunogen

Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) sox2 protein

Immunogen Species

Danio rerio (Zebrafish) (Brachydanio rerio)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Datasheet & COA

Antibody FAQs

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Transcriptional activator. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal.

Gene References into Functions

Findings indicate a pivotal role for ZNF32 function in SOX2 expression and regeneration regulation. PMID:27626680
Both sox2 and p27kip are regulated by the retinoic acid signal pathway and are essential for hair cell regeneration. PMID:26609166
a role of Sox2 as one of the proliferation initiators in ependymal cells after spinal cord injury PMID:25150399
Sox2 is identified as the unknown factor responsible for pineal photoreceptor prepatterning and performs this function independently of the BMP signaling. PMID:24498133
By western blot three protein bands of 28 kDa, 34 kDa (main band), and 38 kDa were detected in the brain of animals 180 days post-fertilizaton. PMID:20734413
significant decreases in sox2 (up to 4-fold) expression following chilling and increase of sox2 (up to 3-fold) during warming of chilled embryos. PMID:21820425
sox2 is required for hair cell survival, as well as for transdifferentiation of support cells into hair cells during regeneration PMID:20025865
shows the occurrence and cell localization of the Sox-2 in chemosensory and mechanosensory organs of zebrafish during the embryonic stage to adult, suggest an involvement of Sox-2 in cell renewal of zebrafish sensory organs PMID:19800392
zebrafish sox2 gene is strongly expressed in neuromast progenitor cells, including those of the migrating lateral line PMID:17443814
Sox2 overlapping transcript has multiple transcription start sites associated with genomic features that indicate regulated expression, including highly conserved elements and chromatin marks characteristic of gene promoters. PMID:19767420

Hide All

Subcellular Location

Nucleus. Cytoplasm.

Tissue Specificity

At the shield stage, expressed uniformly in the future ectoderm. At the 75-80% epiboly stage, becomes localized to the presumptive neuroectoderm; strong expression in the presumptive forebrain, weak expression in the presumptive spinal cord. At the tail b

Database Links

UNIGENE: Dr.5379

KEGG: dre:378723

STRING: 7955.ENSDARP00000095266

Promotions