HTR4 Antibody

Code: CSB-PA010109XA01DOA

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Arabidopsis thaliana

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

P59169

Target Names

HTR4

Alternative Names

HTR4 antibody; At4g40030 antibody; T5J17.200; antibody; HTR5 antibody; At4g40040 antibody; T5J17.210; antibody; HTR8 antibody; At5g10980 antibody; T30N20_250 antibody; T5K6.6Histone H3.3 antibody; Histone H3.2 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana HTR4 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene References into Functions

Gene body methylation is likely shaped by H3.3 dynamics in conjunction with transcriptional activity. PMID:28521766
Clustered pathways are characterized by distinct chromatin signatures of H3K27me3 and H2A.Z, associated with cluster repression and activation, respectively, and represent discrete windows of co-regulation in the genome. PMID:26895889

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Subcellular Location

Nucleus. Chromosome. Nucleus, nucleolus.

Protein Families

Histone H3 family

Tissue Specificity

Ubiquitous.

Database Links

UNIGENE: At.10968

KEGG: ath:AT4G40030

STRING: 3702.AT5G10980.1

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