CDC37 Antibody

Code: CSB-PA005005XA01SVG

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

P06101

Target Names

CDC37

Alternative Names

CDC37 antibody; SMO1 antibody; YDR168W antibody; YD9489.03Hsp90 co-chaperone Cdc37 antibody; Cell division control protein 37 antibody; Hsp90 chaperone protein kinase-targeting subunit antibody

Raised in

Rabbit

Species Reactivity

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Immunogen

Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) CDC37 protein

Immunogen Species

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. Involved in both the HOG and the PKC MAP kinase signaling cascade necessary for adaptation to stress conditions due to high osmolarity or cell wall perturbation.

Gene References into Functions

During cell wall stress, the interaction between Cdc37p, Hog1p, and Hsp90 is crucial for Slt2p-dependent downstream responses to high osmotic and cell wall stress, respectively. PMID:17220467
Cdc37 has a general role in kinome biogenesis PMID:17242065
Kss1p interacts physically with Cdc37p PMID:17451450
There are at least 38 genes having a genetic interaction with a mutant form of the kinase specific chaperone, Cdc37. PMID:18075309
Cdc37p is a part of chaperone system that determins molybdate resistance in Saccharomyces cerevisiae. PMID:19399909