Ace Antibody

Code: CSB-PA001154XA01DLU
Size:
50μl
50μl100μl
US$166
Quantity:
Species Reactivity: Drosophila melanogaster (Fruit fly)
Raised in: Rabbit
Application: ELISA, WB
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Product Details

Uniprot NO.
Target Names
Ace Antibody
Alternative Names
Acetylcholinesterase (AChE) (EC 3.1.1.7) [Cleaved into: Acetylcholinesterase 16 kDa subunit; Acetylcholinesterase 55 kDa subunit] Ace CG17907
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Ace protein (44-293aa)
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Tested Applications
ELISA, WB
Recommended Dilution
ApplicationRecommended Dilution
WB1:500-1:5000
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA
Images
  • Western Blot
    Positive WB detected in: recombinant protein
    All lanes:Ace Antibody at 1:1000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 30 kDa
    Observed band size: 30 kDa

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Rapidly hydrolyzes choline released into the synapse. It can hydrolyze butyrylthiocholine.
Gene References into Functions
  1. 1 engineered disulfide bridge, I327C/D375C increased stability to heat denaturation, urea, & organic solvents & provided protease resistance. The new disulfide bridge links the N-terminal domain (first 356 aa) to the C-terminal domain. PMID:16686937
  2. Results provide insights into substrate and product traffic in the Drosophila melanogaster acetylcholinesterase active site gorge. PMID:18422651
  3. kinetic studies show that it affects interactions with peripheral ligands and the entrance of some of the bulkier substrates PMID:18439026
  4. molecular dynamics simulation reveals the insecticidal resistance mechanism of AChE and its mutation PMID:19263097

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Subcellular Location
Cell junction, synapse. Cell membrane; Lipid-anchor, GPI-anchor. Note=Attached to the membrane of the neuronal cholinergic synapses by a GPI-anchor.
Protein Families
Type-B carboxylesterase/lipase family
Database Links

UNIGENE: Dm.1179

KEGG: dme:Dmel_CG17907

STRING: 7227.FBpp0289713

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No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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