TLR2

Toll-like receptor 2 (TLR2), also known as CD282, is a key protein in the innate immune system. It recognizes a wide range of pathogen - associated molecular patterns (PAMPs) from bacteria, fungi, and parasites. Upon binding to PAMPs, TLR2 activates signaling cascades mainly through the MyD88 - dependent pathway, which leads to the production of pro - inflammatory cytokines.
TLR2 is associated with various diseases such as infectious diseases, autoimmune disorders, and cancer. In cancer, aberrant TLR2 activation may promote tumor growth and metastasis. Currently, there are ongoing efforts in drug development targeting TLR2, aiming to modulate its activity for therapeutic benefits in relevant diseases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP023601HU1 could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) TLR2.

TLR2 Antibody(CSB-PA205006)

Validated Data

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA205006(TLR2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)

Human toll-like receptor 2,TLR2 ELISA Kit(CSB-E11781h)

Validated Data

Code: CSB-E11781h

Size: 96T,5×96T,10×96T

Sensitivity: 0.078 ng/mL

Detection Range: 0.312 ng/mL-20 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following TLR2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TLR2 Antibodies

TLR2 Proteins

TLR2 ELISA Kits

TLR2 Antibodies

TLR2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA023601LD01HU	TLR2 Antibody, Biotin conjugated	Human	ELISA
CSB-PA023601LC01HU	TLR2 Antibody, FITC conjugated	Human
CSB-PA023601LB01HU	TLR2 Antibody, HRP conjugated	Human	ELISA
CSB-PA023601LA01HU	TLR2 Antibody	Human	ELISA
CSB-PA080185	TLR2 Antibody	Human,Mouse,Rat	IHC, ELISA
CSB-PA205006	TLR2 Antibody	Human,Mouse	ELISA,IHC
CSB-PA183593	TLR2 Antibody	Human,Mouse	ELISA,IHC
CSB-RA023601MB1HU	TLR2 (Tomaralimab Biosimilar) Recombinant Monoclonal Antibody	Human

TLR2 Proteins

TLR2 Proteins for Capra ibex (Ibex)

Code	Product Name	Source
CSB-CF023601CZZ	Recombinant Capra ibex Toll-like receptor 2 (TLR2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP023601CZZ1 CSB-EP023601CZZ1 CSB-BP023601CZZ1 CSB-MP023601CZZ1 CSB-EP023601CZZ1-B	Recombinant Capra ibex Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Pan troglodytes (Chimpanzee)

Code	Product Name	Source
CSB-CF023601EQV	Recombinant Pan troglodytes Toll-like receptor 2 (TLR2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP023601EQV1 CSB-EP023601EQV1 CSB-BP023601EQV1 CSB-MP023601EQV1 CSB-EP023601EQV1-B	Recombinant Pan troglodytes Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Pan paniscus (Pygmy chimpanzee) (Bonobo)

Code	Product Name	Source
CSB-CF023601EQU	Recombinant Pan paniscus Toll-like receptor 2 (TLR2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP023601EQU1 CSB-EP023601EQU1 CSB-BP023601EQU1 CSB-MP023601EQU1 CSB-EP023601EQU1-B	Recombinant Pan paniscus Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Equus caballus (Horse)

Code	Product Name	Source
CSB-YP023601HO CSB-EP023601HO CSB-BP023601HO CSB-MP023601HO CSB-EP023601HO-B	Recombinant Horse Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Boselaphus tragocamelus (Nilgai)

Code	Product Name	Source
CSB-YP023601BUN CSB-EP023601BUN CSB-BP023601BUN CSB-MP023601BUN CSB-EP023601BUN-B	Recombinant Boselaphus tragocamelus Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP023601HU1 CSB-EP023601HU1 CSB-BP023601HU1 CSB-MP023601HU1 CSB-EP023601HU1-B	Recombinant Human Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP023601HU1	Recombinant Human Toll-like receptor 2 (TLR2), partial	E.coli
CSB-CF023601HU	Recombinant Human Toll-like receptor 2 (TLR2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Macaca mulatta (Rhesus macaque)

Code	Product Name	Source
CSB-CF023601MOW	Recombinant Macaca mulatta Toll-like receptor 2 (TLR2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP023601MOW1 CSB-EP023601MOW1 CSB-BP023601MOW1 CSB-MP023601MOW1 CSB-EP023601MOW1-B	Recombinant Macaca mulatta (Rhesus macaque) Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Bos indicus (Zebu)

Code	Product Name	Source
CSB-CF023601BUL	Recombinant Bos indicus Toll-like receptor 2 (TLR2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP023601BUL1 CSB-EP023601BUL1 CSB-BP023601BUL1 CSB-MP023601BUL1 CSB-EP023601BUL1-B	Recombinant Bos indicus Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP023601BO CSB-EP023601BO CSB-BP023601BO CSB-MP023601BO CSB-EP023601BO-B	Recombinant Bovine Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Bubalus bubalis (Domestic water buffalo)

Code	Product Name	Source
CSB-YP023601BWX CSB-EP023601BWX CSB-BP023601BWX CSB-MP023601BWX CSB-EP023601BWX-B	Recombinant Bubalus bubalis Toll-like receptor 2 (TLR2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Gorilla gorilla gorilla (Western lowland gorilla)

Code	Product Name	Source
CSB-CF023601GGZ	Recombinant Gorilla gorilla gorilla Toll-like receptor 2 (TLR2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP023601GGZ1 CSB-EP023601GGZ1 CSB-BP023601GGZ1 CSB-MP023601GGZ1 CSB-EP023601GGZ1-B	Recombinant Gorilla gorilla gorilla Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP023601DO CSB-EP023601DO CSB-BP023601DO CSB-MP023601DO CSB-EP023601DO-B	Recombinant Dog Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Ovis aries (Sheep)

Code	Product Name	Source
CSB-CF023601SH	Recombinant Sheep Toll-like receptor 2 (TLR2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP023601SH1 CSB-EP023601SH1 CSB-BP023601SH1 CSB-MP023601SH1 CSB-EP023601SH1-B	Recombinant Sheep Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

Code	Product Name	Source
CSB-YP023601DXU CSB-EP023601DXU CSB-BP023601DXU CSB-MP023601DXU CSB-EP023601DXU-B	Recombinant Cricetulus griseus Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-YP023601MOV CSB-EP023601MOV CSB-BP023601MOV CSB-MP023601MOV CSB-EP023601MOV-B	Recombinant Macaca fascicularis Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Giraffa camelopardalis (Giraffe)

Code	Product Name	Source
CSB-CF023601GGC	Recombinant Giraffa camelopardalis Toll-like receptor 2 (TLR2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP023601GGC1 CSB-EP023601GGC1 CSB-BP023601GGC1 CSB-MP023601GGC1 CSB-EP023601GGC1-B	Recombinant Giraffa camelopardalis Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Bison bison (American bison) (Bos bison)

Code	Product Name	Source
CSB-CF023601BTE	Recombinant Bison bison Toll-like receptor 2 (TLR2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP023601BTE1 CSB-EP023601BTE1 CSB-BP023601BTE1 CSB-MP023601BTE1 CSB-EP023601BTE1-B	Recombinant Bison bison Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP023601MO CSB-EP023601MO CSB-BP023601MO CSB-MP023601MO CSB-EP023601MO-B	Recombinant Mouse Toll-like receptor 2 (Tlr2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Capra hircus (Goat)

Code	Product Name	Source
CSB-YP023601GO CSB-EP023601GO CSB-BP023601GO CSB-MP023601GO CSB-EP023601GO-B	Recombinant Goat Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 ELISA Kit

TLR2 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E11781h	Human toll-like receptor 2,TLR2 ELISA Kit	serum, plasma, tissue homogenates	0.078 ng/mL

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TLR2

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