TGFBR1

TGFBR1, also referred to as Transforming Growth Factor Beta Receptor 1 or ALK5, is a serine/threonine kinase receptor encoded by a human gene. It serves as an essential part of the TGF-beta signaling pathway, interacting with TGF-beta ligands to initiate various signaling cascades, including the Smad pathway. This activation modulates cell behaviors such as proliferation, differentiation, migration, and apoptosis. TGFBR1 is crucial for processes like embryonic development, tissue repair, immune system regulation, and the formation of tumors. Its malfunction is associated with conditions such as fibrosis and various cancers, making it a potential target for pharmaceutical intervention and therapeutic strategies.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TGFBR1 Antibody(CSB-PA004276)

Validated Data

Western Blot analysis of HepG2 cells using TGFβ RI Polyclonal Antibody

Western Blot analysis of NIH-3T3 cells using TGFβ RI Polyclonal Antibody

The following TGFBR1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TGFBR1 Antibodies

TGFBR1 Proteins

TGFBR1 Antibodies

TGFBR1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA061850	TGFBR1 (Ab-165) Antibody	Human,Mouse	ELISA,WB,IF
CSB-PA004276	TGFBR1 Antibody	Human,Mouse,Rat	WB, IF, ELISA
CSB-PA050248	Phospho-TGFBR1 (S165) Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA699479	TGFBR1 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA206147	TGFBR1 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA023451LA01HU	TGFBR1 Antibody	Human	ELISA, WB, IHC, IF
CSB-PA023451LB01HU	TGFBR1 Antibody, HRP conjugated	Human	ELISA
CSB-PA023451LC01HU	TGFBR1 Antibody, FITC conjugated	Human
CSB-PA023451LD01HU	TGFBR1 Antibody, Biotin conjugated	Human	ELISA

TGFBR1 Proteins

TGFBR1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP023451HU1 CSB-EP023451HU1 CSB-BP023451HU1 CSB-MP023451HU1 CSB-EP023451HU1-B	Recombinant Human TGF-beta receptor type-1 (TGFBR1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF023451HU	Recombinant Human TGF-beta receptor type-1 (TGFBR1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP023451HU1	Recombinant Human TGF-beta receptor type-1 (TGFBR1), partial	E.coli
CSB-MP023451HU2	Recombinant Human TGF-beta receptor type-1 (TGFBR1), partial	Mammalian cell
CSB-EP023451HU1-B	Recombinant Human TGF-beta receptor type-1 (TGFBR1), partial, Biotinylated	E.coli

TGFBR1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP023451RA CSB-EP023451RA CSB-BP023451RA CSB-MP023451RA CSB-EP023451RA-B	Recombinant Rat TGF-beta receptor type-1 (Tgfbr1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TGFBR1 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP685610PI CSB-EP685610PI CSB-BP685610PI CSB-MP685610PI CSB-EP685610PI-B	Recombinant Pig TGF-beta receptor type-1 (TGFBR1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TGFBR1 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-CF023451BO	Recombinant Bovine TGF-beta receptor type-1 (TGFBR1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP023451BO1 CSB-EP023451BO1 CSB-BP023451BO1 CSB-MP023451BO1 CSB-EP023451BO1-B	Recombinant Bovine TGF-beta receptor type-1 (TGFBR1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TGFBR1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP734134MO CSB-EP734134MO CSB-BP734134MO CSB-MP734134MO CSB-EP734134MO-B	Recombinant Mouse TGF-beta receptor type-1 (Tgfbr1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

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TGFBR1

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