SHANK3

SH3 and multiple ankyrin repeat domains protein 3 is a protein in humans that is encoded by SHANK3 gene. Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance. Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters.

The following SHANK3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

SHANK3 Proteins

SHANK3 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP880134HU CSB-EP880134HU CSB-BP880134HU CSB-MP880134HU CSB-EP880134HU-B	Recombinant Human SH3 and multiple ankyrin repeat domains protein 3 (SHANK3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP880134HU	Recombinant Human SH3 and multiple ankyrin repeat domains protein 3 (SHANK3), partial	E.coli
CSB-MP880134HU	Recombinant Human SH3 and multiple ankyrin repeat domains protein 3 (SHANK3), partial	Mammalian cell
CSB-MP880134HUq10	Recombinant Human SH3 and multiple ankyrin repeat domains protein 3 (SHANK3), partial	Mammalian cell

SHANK3 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP872887RA CSB-EP872887RA CSB-BP872887RA CSB-MP872887RA CSB-EP872887RA-B	Recombinant Rat SH3 and multiple ankyrin repeat domains protein 3 (Shank3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SHANK3 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP674485MO CSB-EP674485MO CSB-BP674485MO CSB-MP674485MO CSB-EP674485MO-B	Recombinant Mouse SH3 and multiple ankyrin repeat domains protein 3 (Shank3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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