NF2

Neurofibromatosis type 2 (NF2) stems from mutations in the NF2 gene on chromosome 22. This gene encodes the Merlin protein, functions as tumor suppressor properties. NF2 mutations can impair the Merlin protein's function, reducing its tumor-inhibiting capabilities and increasing susceptibility to nervous system tumors such as vestibular schwannoma and meningioma. NF2 exemplifies the connection between genetic mutations and the development of nervous system tumors, providing valuable insights for diagnosis, treatment, and genetic counseling.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

NF2 Antibody(CSB-PA015741LA01HU)

Validated Data

Western Blot
Positive WB detected in: HEK293 whole cell lysate, Jurkat whole cell lysate, MCF-7 whole cell lysate, NIH/3T3 whole cell lysate
All lanes: NF2 antibody at 2.6μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 70, 73, 60, 65, 64, 31, 66, 20, 25 kDa
Observed band size: 70, 73 kDa

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA015741LA01HU at dilution of 1:100

Immunofluorescent analysis of Hela cells using CSB-PA015741LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

The following NF2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

NF2 Antibodies

NF2 Proteins

NF2 Antibodies

NF2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA015741GA01HU	NF2 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA149148	Phospho-NF2 (Ser518) Antibody	Human,Mouse,Rat	ELISA,WB,IF
CSB-PA779103	NF2 (Ab-518) Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA249373	NF2 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA003420	NF2 Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA020074	Phospho-NF2 (S518) Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA020075	Phospho-NF2 (S10) Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA020077	NF2 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA015741LA01HU	NF2 Antibody	Human, Mouse	ELISA, WB, IHC, IF
CSB-PA015741LB01HU	NF2 Antibody, HRP conjugated	Human	ELISA
CSB-PA015741LC01HU	NF2 Antibody, FITC conjugated	Human
CSB-PA015741LD01HU	NF2 Antibody, Biotin conjugated	Human	ELISA

NF2 Antibodies for Mus musculus (Mouse)

Code	Product Name	Species Reactivity	Application
CSB-PA015741ZA01MO	Nf2 Antibody	Mus musculus	ELISA, WB (ensure identification of antigen)

NF2 Proteins

NF2 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP726923RA CSB-EP726923RA CSB-BP726923RA CSB-MP726923RA CSB-EP726923RA-B	Recombinant Rat Merlin (Nf2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NF2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP015741HU CSB-EP015741HU CSB-BP015741HU CSB-MP015741HU CSB-EP015741HU-B	Recombinant Human Merlin (NF2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP015741HU	Recombinant Human Merlin (NF2)	E.coli

NF2 Proteins for Papio anubis (Olive baboon)

Code	Product Name	Source
CSB-YP015741ERI CSB-EP015741ERI CSB-BP015741ERI CSB-MP015741ERI CSB-EP015741ERI-B	Recombinant Papio anubis Merlin (NF2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

NF2 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP015741MO1 CSB-EP015741MO1 CSB-BP015741MO1 CSB-MP015741MO1 CSB-EP015741MO1-B	Recombinant Mouse Merlin (Nf2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP015741MO1	Recombinant Mouse Merlin (Nf2), partial	E.coli

Promotions

Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

Apoptosis mediated by mitochondria The Overview of Hippo Signaling Pathway The Overview of Autophagy Crosstalk Between Autophagy and Apoptosis The Overview of Wnt Signaling Pathway The Overview of Breast Cancer: Related Signaling Pathways, Therapeutic Targets The overview of TGF-β signaling pathway PI3K-Akt Signaling Pathway and Cancer Apoptosis mediated by endoplasmic reticulum Apoptosisi mediated by death receptor Aesthetic Appreciation of Apoptosis Signal Pathway An Overview of Cell Death: Necrosis and Apoptosis Do You Really Know TGF-β Superfamily?Double-Edged Sword: TGF-β The Overview of PI3-Alt Signaling Pathway How to Inquire and Utilize the Signal Pathway on KEGG LPS/TLR4 Signal Transduction Pathway Epigenetic Histone Modifications Pathway What A Paradoxical TNF Signaling Pathway-Based on Different Receptors The Overview of Fc Receptors- Classification, Related Signaling Pathways and Application

NF2

Popular Product: