GDF15

GDF15, a member of the TGFβ superfamily and also known as MIC-1 and PDF, functions as a stress response protein with key roles in various disease pathways. By binding to GFRAL-RET receptors, GDF15 regulates physiological processes including appetite, body weight, insulin sensitivity, and inflammatory responses. Its elevated levels in tumors, cardiovascular, and metabolic diseases position it as a potential biomarker and a novel target for therapeutic development. GDF15-targeted therapies are emerging as a cutting-edge area of research, aiming to offer innovative treatment strategies by modulating GDF15 expression levels.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

GDF15 Recombinant Monoclonal Antibody(CSB-RA285852A0HU)

Validated Data

IHC image of CSB-RA285852A0HU diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

The following GDF15 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

GDF15 Antibodies

GDF15 Proteins

GDF15 ELISA Kits

GDF15 Antibodies

GDF15 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA10029B0Rb	GDF15 Antibody, HRP conjugated	Human	ELISA
CSB-PA10029D0Rb	GDF15 Antibody, Biotin conjugated	Human	ELISA
CSB-PA10029A0Rb	GDF15 Antibody	Human	ELISA, WB, IHC
CSB-PA563663	GDF15 Antibody	Human	ELISA,WB
CSB-PA002673	GDF15 Antibody	Human	WB, ELISA
CSB-PA779597	GDF15 Antibody	Human,Mouse	ELISA,WB
CSB-PA255283	GDF15 Antibody	Human	ELISA,IHC
CSB-MA999881A0m	GDF15 Monoclonal Antibody	Human	ELISA,IHC
CSB-RA285852A0HU	GDF15 Recombinant Monoclonal Antibody	Human	ELISA, IHC
CSB-RA859530MA1HU	GDF15 Recombinant Monoclonal Antibody	Human	ELISA, IHC
CSB-RA859530MB1HU	GDF15 (visugromab Biosimilar) Recombinant Monoclonal Antibody	Human
CSB-RA859530MB2HU	GDF15 (Ponsegromab Biosimilar) Recombinant Monoclonal Antibody	Human
CSB-RA859530MB3HU	GDF15 (Rilogrotug Biosimilar) Recombinant Monoclonal Antibody	Human

GDF15 Proteins

GDF15 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-EP859530HU	Recombinant Human Growth/differentiation factor 15 (GDF15), partial	E.coli
CSB-YP859530HU CSB-EP859530HU CSB-BP859530HU CSB-MP859530HU CSB-EP859530HU-B	Recombinant Human Growth/differentiation factor 15 (GDF15), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP859530HU1	Recombinant Human Growth/differentiation factor 15 (GDF15), partial	E.coli
CSB-EP859530HU1c7	Recombinant Human Growth/differentiation factor 15 (GDF15), partial	E.coli

GDF15 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-EP3466MO	Recombinant Mouse Growth/differentiation factor 15 (Gdf15)	E.coli
CSB-MP859530MO	Recombinant Mouse Growth/differentiation factor 15 (Gdf15)	Mammalian cell